Evidence map›Paper›PMID 29681999›Full record

ArticleComputational and mathematical methods in medicine2018

Numerical Simulations of the Motion and Deformation of Three RBCs during Poiseuille Flow through a Constricted Vessel Using IB-LBM.

Rongyang Wang, Yikun Wei, Chuanyu Wu, Liang Sun, Wenguang Zheng

Abstract read
In one paragraph

Article in Computational and mathematical methods in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rongyang WangFaculty of Mechanical Engineering and Automation, Zhejiang Sci-Tech University, Hangzhou 310018, China.ORCID 0000-0001-6806-0876
Yikun WeiFaculty of Mechanical Engineering and Automation, Zhejiang Sci-Tech University, Hangzhou 310018, China.ORCID 0000-0002-5462-1502
Chuanyu WuFaculty of Mechanical Engineering and Automation, Zhejiang Sci-Tech University, Hangzhou 310018, China.ORCID 0000-0003-4951-6502
Liang SunFaculty of Mechanical Engineering and Automation, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Wenguang ZhengFaculty of Mechanical Engineering and Automation, Zhejiang Sci-Tech University, Hangzhou 310018, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immersed boundary-lattice Boltzmann method (IB-LBM) was used to examine the motion and deformation of three elastic red blood cells (RBCs) during Poiseuille flow through constricted microchannels. The objective was to determine the effects of the degree of constriction and the Reynolds (Re) number of the flow on the physical characteristics of the RBCs. It was found that, with decreasing constriction ratio, the RBCs experienced greater forced deformation as they squeezed through the constriction area compared to at other parts of the microchannel. It was also observed that a longer time was required for the RBCs to squeeze through a narrower constriction. The RBCs subsequently regained a stable shape and gradually migrated toward the centerline of the flow beyond the constriction area. However, a sick RBC was observed to be incapable of passing through a constricted vessel with a constriction ratio ≤1/3 for Re numbers below 0.40.

Indexed as

Biomechanical PhenomenaComputational BiologyComputer SimulationConstriction, PathologicElastic ModulusErythrocyte DeformabilityErythrocytesErythrocytes, AbnormalHemorheologyHumansMicrovesselsModels, BiologicalModels, CardiovascularMotion

Identifiers

PMID29681999
PMCPMC5841101

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.