Evidence map›Paper›PMID 29681986›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

Anti-Inflammatory Effect of Feiyangchangweiyan Capsule on Rat Pelvic Inflammatory Disease through JNK/NF-

Yao Li, Yang Liu, Qian Yang, Zhihui Shi, Yanhua Xie, Siwang Wang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yao LiSchool of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712000, China.
Yang LiuCollege of Chemistry and Pharmacy, Northwest Agriculture and Forestry University, Yangling 712100, China.
Qian YangDepartment of Natural Medicine, School of Pharmacy, The Fourth Military Medical University, Xi'an 710032, China.
Zhihui ShiShaanxi Junbisha Pharmaceutical Limited Company, Shaanxi, China.
Yanhua XieDepartment of Natural Medicine, School of Pharmacy, The Fourth Military Medical University, Xi'an 710032, China.ORCID 0000-0002-0834-265X
Siwang WangDepartment of Natural Medicine, School of Pharmacy, The Fourth Military Medical University, Xi'an 710032, China.ORCID 0000-0003-1888-4716
Air Force Medical University · CNNorthwest A&F University · CNShaanxi University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn this study, we aimed to illustrate the preventive effect and possible mechanisms of Feiyangchangweiyan capsule (FYCWYC) on rat pelvic inflammatory disease (PID) model.

methodsTo construct the rat PID model, upper genital tract was infected by multipathogen, and then drugs were orally administered for 8 days. The histological examination, immunohistochemical analysis, and ELISA were carried out. Furthermore, Western blotting was used to analyze the expression of Akt, MAPKs, NF-

resultsAs the results showed, infiltrations of neutrophils and lymphocytes in uterus were significantly suppressed, and IL-1

conclusionsTaken together, our results demonstrated that FYCWYC had anti-inflammatory effect in pathogen-induced PID model, and the mechanism might be through inhibiting NF-

Identifiers

PMID29681986
PMCPMC5851019
OpenAlexW2793861838

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.