ArticleKardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery2018
Levosimendan in patients with low ejection fraction undergoing cardiac surgery.
Article in Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors at 2 institutions in 1 country.
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Abstract
introductionSignificant impairment of left ventricular function causes low cardiac output syndrome in the immediate postoperative period in 3-14% of patients undergoing surgery, increasing the mortality 15-fold.
aimTo assess the use of levosimendan in patients undergoing cardiac surgery in 2016. MATERIAL AND
methodsThe analysis included 14 patients: 3 (21.4%) women and 11 (78.6%) men aged 65.4 ±11.8 years. The mean value of left ventricular ejection fraction amounted to 20 ±6.25%. In 11 patients, levosimendan infusion was started immediately after the induction of anesthesia. Three patients received the agent during the early postoperative period due to low cardiac output syndrome refractory to conventional therapy. The dosage was modified within the range of 0.05-0.2 μg/kg/min. On the day of the surgery, all patients received continuous infusion of adrenaline and levonor.
resultsThe cardiac index amounted to 2.8 ±0.71 l/m
conclusionsLevosimendan therapy proved safe in the study group. The nature of the study and the small sample size preclude the formulation of detailed conclusions.
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