Evidence map›Paper›PMID 29681497›Full record

ArticleMolecular cell2018

CapZyme-Seq Comprehensively Defines Promoter-Sequence Determinants for RNA 5' Capping with NAD<sup/>.

Irina O Vvedenskaya, Jeremy G Bird, Yuanchao Zhang, Yu Zhang, Xinfu Jiao, Ivan Barvík, Libor Krásný, Megerditch Kiledjian, Deanne M Taylor, Richard H Ebright and 1 more

Abstract read
In one paragraph

Article in Molecular cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. 5'-terminal glycosylation of protein-coding transcripts: An epitranscriptomic modification that prolongs mRNA lifetimes.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Co-transcriptional gene regulation in eukaryotes and prokaryotes.Nature reviews. Molecular cell biology · 2024
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Irina O VvedenskayaDepartment of Genetics and Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA.
Jeremy G BirdDepartment of Genetics and Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA; Department of Chemistry and Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA.
Yuanchao ZhangDepartment of Genetics and Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA; Department of Biomedical and Health Informatics, Children's Hospital, Philadelphia, PA 19041, USA.
Yu ZhangKey Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China.
Xinfu JiaoDepartment of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854, USA.
Ivan BarvíkDivision of Biomolecular Physics, Institute of Physics, Faculty of Mathematics and Physics, Charles University, Ke Karlovu 5, 12116 Prague 2, Czech Republic.
Libor KrásnýInstitute of Microbiology, Czech Academy of Sciences, v.v.i., Vídeňská 1083, 14220 Prague 4, Czech Republic.
Megerditch KiledjianDepartment of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854, USA.
Deanne M TaylorDepartment of Genetics and Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA; Department of Biomedical and Health Informatics, Children's Hospital, Philadelphia, PA 19041, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Obstetrics, Gynecology and Reproductive Sciences, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.
Richard H EbrightDepartment of Chemistry and Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA. Electronic address: ebright@waksman.rutgers.edu.
Bryce E NickelsDepartment of Genetics and Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA. Electronic address: bnickels@waksman.rutgers.edu.

Funding

Transcription: Mechanism and RegulationR35GM118059 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI NICKELS, BRYCE EDWARD · 2016 to 2025
$7.1M
TRANSCRIPTION ACTIVATION BY CAPR01GM041376 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI RICHARD H. EBRIGHT · 1989 to 2026
$6.5M
Regulation of Mammalian mRNA DecayR01GM067005 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI KILEDJIAN, MEGERDITCH · 2004 to 2022
$5.5M
BACTERIAL TRANSCRIPTION COMPLEXESR37GM041376 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI EBRIGHT, RICHARD H. · 2013 to 2022
$5.0M
NIGMS NIH HHS R01 GM041376NIGMS NIH HHS R01 GM067005NIGMS NIH HHS R35 GM118059NIGMS NIH HHS R37 GM041376
6 · The paper itself

Abstract

Nucleoside-containing metabolites such as NAD

Indexed as

DNA-Directed RNA PolymerasesEndoribonucleasesEscherichia coliGene ExpressionHigh-Throughput Nucleotide SequencingNADNucleotidesPromoter Regions, GeneticRNA CapsTranscription, GeneticTranscription Initiation SiteTranscriptomeDNA-Directed RNA PolymerasesEndoribonucleasesmRNA decapping enzymesNADNucleotidesRNA Capsnicotinamide adenine dinucleotidenon-canonical initiating nucleotideNudCRai1RNA cappingRNA polymeraseRNA-seqtranscriptiontranscription initiationtranscription start site

Identifiers

PMID29681497
PMCPMC5935523

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.