Evidence map›Paper›PMID 29681423›Full record

ArticleUltrasound in medicine & biology2018

Ultrasonic Cavitation-Enabled Treatment for Therapy of Hypertrophic Cardiomyopathy: Proof of Principle.

Douglas L Miller, Xiaofang Lu, Chunyan Dou, Yiying I Zhu, Rachael Fuller, Kristina Fields, Mario L Fabiilli, Gabe E Owens, David Gordon, Oliver D Kripfgans

Abstract read
In one paragraph

Article in Ultrasound in medicine & biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Overview of Therapeutic Ultrasound Applications and Safety Considerations: 2024 Update.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025
    Review
  4. Role of Ultrasound-Based Therapies in Cardiovascular Diseases.Structural heart : the journal of the Heart Team · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Douglas L MillerUniversity of Michigan Health System, Ann Arbor, Michigan, USA. Electronic address: douglm@umich.edu.
Xiaofang LuUniversity of Michigan Health System, Ann Arbor, Michigan, USA.
Chunyan DouUniversity of Michigan Health System, Ann Arbor, Michigan, USA.
Yiying I ZhuUniversity of Michigan Health System, Ann Arbor, Michigan, USA.
Rachael FullerUniversity of Michigan Health System, Ann Arbor, Michigan, USA.
Kristina FieldsUniversity of Michigan Health System, Ann Arbor, Michigan, USA.
Mario L FabiilliUniversity of Michigan Health System, Ann Arbor, Michigan, USA.
Gabe E OwensUniversity of Michigan Health System, Ann Arbor, Michigan, USA.
David GordonUniversity of Michigan Health System, Ann Arbor, Michigan, USA.
Oliver D KripfgansUniversity of Michigan Health System, Ann Arbor, Michigan, USA.
Michigan Medicine · US

Funding

Therapeutic Microlesioning by Contrast Echocardiography for Myocardial ReductionR01HL114595 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KRIPFGANS, OLIVER D · 2012 to 2016
$1.9M
NHLBI NIH HHS R01 HL114595
6 · The paper itself

Abstract

Ultrasound myocardial cavitation-enabled treatment was applied to the SS-16

Indexed as

AnimalsCardiomyopathy, HypertrophicDisease Models, AnimalRatsRats, Inbred DahlTreatment OutcomeUltrasonic TherapyCardiac fibrosisCardiac myocyte necrosisHypertrophic cardiomyopathyMyocardial contrast echocardiographyUltrasonic cavitation

Identifiers

PMID29681423
PMCPMC5960614
OpenAlexW2801502539

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.