ReviewCurrent cardiology reports2018
Current State of Left Atrial Appendage Closure.
Review in Current cardiology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Surgical Methods and Devices for Atrial Fibrillation.Reviews in cardiovascular medicine · 2025Review
- Left Atrial Appendage Closure with the LAmbre Device - Initial Multicentre Experience in Brazil.Arquivos brasileiros de cardiologia · 2022Article
- Watchman outcomes comparing post-implantation anticoagulation with warfarin versus direct oral anticoagulants.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021Article
- Preclinical Assessment of a Novel Conformable Foam-Based Left Atrial Appendage Closure Device.BioMed research international · 2021Article
- Treatment of atrial fibrillation: a comprehensive review and practice guide.Cardiovascular journal of AfricaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewAtrial fibrillation (AF), the most common sustained arrhythmia, is a major cause of stroke and systemic embolism, and is increasing in prevalence. Device closure of the left atrial appendage (LAA) represents a non-pharmacologic approach to stroke prevention in AF patients. This review presents the rationale for LAA closure (LAAC), describes current transcatheter approaches to LAAC, and summarizes the current evidence for LAAC for stroke prevention, highlighting the main randomized trials and the most recent data available. RECENT
findingsMeta-analysis of randomized clinical trials demonstrates similar rates of all-cause stroke with transcatheter LAAC compared with vitamin K antagonist therapy and significantly less bleeding with LAAC after cessation of mandated post-procedure pharmacology. Recent prospective observational studies, including those evaluating outcomes after commercial approval in the USA, show significantly improved procedure safety compared with earlier experiences. LAAC appears to be an attractive alternative strategy for stroke prevention in AF patients, particularly in those who can take short-term oral anticoagulation (OAC), but are not optimal candidates for long-term OAC. Recent data suggests the procedure can be safely performed in patients with contraindications to OAC. Further, robust studies are needed to evaluate safety and efficacy in OAC-contraindicated patients, to compare outcomes with non-vitamin K antagonist OACs, and to explore the relative safety and efficacy of different LAAC devices.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.