Evidence map›Paper›PMID 29680980›Full record

ReviewClinical journal of gastroenterology2018

When a cure becomes the pathology: mechanical bowel obstruction due to herbal pharmacobezoar. A case report with review of literature.

Saurabh Gandhi, Eham Arora, Ajay Bhandarwar, Arun Patil, Amol Wagh, Shubham Gupta

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Clinical journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Gastro-esophageal pharmacobezoar.Forensic science, medicine, and pathology · 2021
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Saurabh GandhiDepartment of General Surgery, Grant Government Medical College and Sir JJ Group of Hospitals, 6th Floor, Main Hospital Building, JJ Hospital Campus, Sir JJ Marg, Byculla, Mumbai, 400008, India.
Eham AroraDepartment of General Surgery, Grant Government Medical College and Sir JJ Group of Hospitals, 6th Floor, Main Hospital Building, JJ Hospital Campus, Sir JJ Marg, Byculla, Mumbai, 400008, India. ehamarora@gmail.com.ORCID http://orcid.org/0000-0002-5120-3356
Ajay BhandarwarDepartment of General Surgery, Grant Government Medical College and Sir JJ Group of Hospitals, 6th Floor, Main Hospital Building, JJ Hospital Campus, Sir JJ Marg, Byculla, Mumbai, 400008, India.
Arun PatilDepartment of General Surgery, Grant Government Medical College and Sir JJ Group of Hospitals, 6th Floor, Main Hospital Building, JJ Hospital Campus, Sir JJ Marg, Byculla, Mumbai, 400008, India.
Amol WaghDepartment of General Surgery, Grant Government Medical College and Sir JJ Group of Hospitals, 6th Floor, Main Hospital Building, JJ Hospital Campus, Sir JJ Marg, Byculla, Mumbai, 400008, India.
Shubham GuptaDepartment of General Surgery, Grant Government Medical College and Sir JJ Group of Hospitals, 6th Floor, Main Hospital Building, JJ Hospital Campus, Sir JJ Marg, Byculla, Mumbai, 400008, India.
Government Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bezoars are intra-luminal concretions of ingested material which accumulate within the bowel. They are termed pharmacobezoars when the constituent material is drugs. We report a 64-year-old female with abdominal pain and obstipation for 3 days. Patient had completed anti-tuberculous combination therapy for suspected abdominal tuberculosis 25 years ago. She exhibited features of shock with a right iliac fossa lump. Abdominal X-ray displayed multiple air-fluid levels with densely cluttered radio-opacities in the right lower quadrant. Laparotomy revealed a palpable mid-ileal intra-luminal lump, adherent to the ascending colon and proximal ileum necessitating resection. Ex vivo examination of resected specimen revealed numerous tablets aggregating proximal to an ileal stricture. The patient post-operatively confirmed the tablets resembled the herbal laxatives she had been consuming. Pharmacobezoars can lead to subacute intestinal obstruction. Numerous drugs have been implicated. Patients with partial gastrectomy and vagotomy are at risk. CT is the pre-eminent diagnostic modality. The treatment options for pharmacobezoars include lavage, endoscopic retrieval, in addition to surgery. Pharmacobezoars need a high index of suspicion for pre-operative diagnosis. A detailed history and correlation with radioimaging can offer important cues. One can prevent pharmacobezoars by abstaining from unwarranted medications and identifying those at risk.

Indexed as

Abdominal PainBezoarsConstipationFemaleHumansIleal DiseasesIntestinal ObstructionLaxativesMiddle AgedPlant PreparationsTabletsLaxativesPlant PreparationsTabletsAbdominal tuberculosisBezoarIntestinal obstructionPharmacobezoar

Identifiers

PMID29680980
OpenAlexW2800680561

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.