SynthesisInternational journal of colorectal disease2018
Towards a core outcome set for hemorrhoidal disease-a systematic review of outcomes reported in literature.
Synthesis in International journal of colorectal disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Real-world use of polidocanol foam sclerotherapy for hemorrhoidal disease: insights from an international survey and systematic review with clinical practice recommendations.Updates in surgery · 2025Pooled it
- Identifying outcomes reported in exercise interventions in oesophagogastric cancer survivors: a systematic review.BMC cancer · 2021Pooled it
- Scoring systems as outcomes assessment of the treatments for haemorrhoidal disease: a systematic review of the literature.International journal of colorectal disease · 2020Pooled it
- Heterogeneous outcome reporting in adult slow-transit constipation studies: Systematic review towards a core outcome set.Journal of gastroenterology and hepatology · 2020Pooled it
- Radiofrequency Ablation for Hemorrhoidal Disease.Life (Basel, Switzerland) · 2026Review
- Polidocanol foam sclerotherapy in hemorrhoidal disease: shifting the focus to symptom relief, safety and repeatability.Updates in surgery · 2026Article
- Polidocanol foam for hemorrhoids: promising, yet premature without long-term evidence.Updates in surgery · 2026Article
- Editorial: Haemorrhoidal Disease: Old solutions and future perspectives Volume II.Frontiers in surgery · 2025Article
- Article
- Time to change? Present and prospects of hemorrhoidal classification.Frontiers in medicine · 2023Review
- Patient reported outcome measure-haemorrhoidal impact and satisfaction score (PROM-HISS): Development, reliability and construct validity.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022Article
- Editorial: Haemorrhoidal Disease: Old Solutions and Future Perspectives.Frontiers in surgery · 2022Article
- Proposal for a New Score: Hemorrhoidal Bleeding Score.Annals of coloproctology · 2021Article
- A Stepwise Proposal for Low-Grade Hemorrhoidal Disease: Injection Sclerotherapy as a First-Line Treatment and Rubber Band Ligation for Persistent Relapses.Frontiers in surgery · 2021Review
- [Quality indicators in the treatment of hemorrhoids].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2019Review
- Outcome Selection and Methodological Quality of Major and Minor Shoulder Surgery Studies: A Scoping Review.Clinical orthopaedics and related research · 2019Article
- A validated severity score for haemorrhoids as an essential prerequisite for future haemorrhoid trials.Techniques in coloproctology · 2019Article
- Offering HeLP to work out the optimum treatment for haemorrhoidal disease.Techniques in coloproctology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePreviously published literature regarding treatment of hemorrhoidal disease (HD) revealed a lack of uniform defined outcomes. These differences between outcomes among studies limit transparency and lead to incomparability of results. The aim of this study was to systematically list the types of outcomes used in HD studies. This list will be used to develop a core outcome set.
methodsWe searched Medline (Pubmed), Embase (OVID), and Cochrane for interventional studies for adult patients with HD. Two authors independently identified and reviewed eligible studies. This resulted in a list of outcomes reported by each clinical trial. All outcomes were categorized using the conceptual framework OMERACT filter 2.0.
resultsA total of 34 randomized controlled trials and prospective observational studies were included in this study. A total of 59 different types of outcomes were identified. On average, 5.8 different outcomes (range 2-8) were used per study. The outcomes were structured into three core areas and10 ten domains. The most commonly reported core area was pathophysiological manifestations including the domain symptoms, complications, and recurrence. The most frequently reported outcomes were pain (91%), blood loss (94%), prolapse (71%), and incontinence (56%). There was a high variation in definitions of the common outcomes. And often there was no definition at all.
conclusionThis study shows a substantial heterogeneity in the types of outcomes in HD studies. We provided an overview of the types of outcomes reported in HD studies and identified a list of potentially relevant outcomes required for the development of a COS.
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