Evidence map›Paper›PMID 29680824›Full record

ArticleJournal of the American Heart Association2018

DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran Program.

Luc Djoussé, Yuk-Lam Ho, Xuan-Mai T Nguyen, David R Gagnon, Peter W F Wilson, Kelly Cho, J Michael Gaziano, VA Million Veteran Program

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04331535 (Pragmatic Randomized Trial of Polygenic Risk Scoring for Common Diseases in Primary Care), which is not on this map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04331535 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Pragmatic Randomized Trial of Polygenic Risk Scoring for Common Diseases in Primary Care

TypeinterventionalSponsorBoston VA Research Institute, Inc.Ran2020 to 2025Enrolled1,076ConditionsCoronary Artery Disease, Atrial Fibrillation, Type 2 Diabetes, Colorectal CancerArmsPolygenic risk score (PRS)
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 18 institutions in 6 countries.

Luc DjousséMassachussets Veterans Epidemiology Research and Information Center, Boston VA Healthcare System, Boston, MA Ldjousse@rics.bwh.harvard.edu.
Yuk-Lam HoMassachussets Veterans Epidemiology Research and Information Center, Boston VA Healthcare System, Boston, MA.
Xuan-Mai T NguyenMassachussets Veterans Epidemiology Research and Information Center, Boston VA Healthcare System, Boston, MA.
David R GagnonMassachussets Veterans Epidemiology Research and Information Center, Boston VA Healthcare System, Boston, MA.
Peter W F WilsonAtlanta VA Healthcare System and Emory School of Medicine, Atlanta, GA.
Kelly ChoMassachussets Veterans Epidemiology Research and Information Center, Boston VA Healthcare System, Boston, MA.
J Michael GazianoMassachussets Veterans Epidemiology Research and Information Center, Boston VA Healthcare System, Boston, MA.
VA Million Veteran Program
Harvard University · USAtlanta VA Health Care System · USVA Boston Healthcare System · USAdrian College · USA.P. Karpinsky Russian Geological Research Institute · RUBoston University · USCallaghan Innovation · NZHarley-Davidson (United States) · USHermes Arzneimittel (Germany) · DEJack Miller Center · USJeffrey Modell Foundation · AUKlein Buendel (United States) · USMeyer Werft (Germany) · DERichard Wolf (Germany) · DESharma & Associates (United States) · USSherman Hospital · USSun Chemical (United States) · USThomas Swan (United Kingdom) · GB

Funding

Cardiovascular Disease Risk Factors, Prevalent Cardiovascular Disease, and Genetics in the Million Veteran ProgramI01BX003340 · VA · VETERANS HEALTH ADMINISTRATION · PI CHO, KELLY, WILSON, PETER WYMAN · 2017 to 2017
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BLRD VA I01 BX003340CSRD VA I01 CX001025
6 · The paper itself

Abstract

backgroundWhile adherence to healthful dietary patterns has been associated with a lower risk of coronary artery disease (CAD) in the general population, limited data are available among US veterans. We tested the hypothesis that adherence to Dietary Approach to Stop Hypertension (DASH) food pattern is associated with a lower risk of developing CAD among veterans. METHODS AND

resultsWe analyzed data on 153 802 participants of the Million Veteran Program enrolled between 2011 and 2016. Information on dietary habits was obtained using a food frequency questionnaire at enrollment. We used electronic health records to assess the development of CAD during follow-up. Of the 153 802 veterans who provided information on diet and were free of CAD at baseline, the mean age was 64.0 (SD=11.8) years and 90.4% were men. During a mean follow-up of 2.8 years, 5451 CAD cases occurred. The crude incidence rate of CAD was 14.0, 13.1, 12.6, 12.3, and 11.1 cases per 1000 person-years across consecutive quintiles of Dietary Approach to Stop Hypertension score. Hazard ratios (95% confidence interval) for CAD were 1.0 (ref), 0.91 (0.84-0.99), 0.87 (0.80-0.95), 0.86 (0.79-0.94), and 0.80 (0.73-0.87) from the lowest to highest quintile of Dietary Approach to Stop Hypertension score controlling for age, sex, body mass index, race, smoking, exercise, alcohol intake, and statin use (

conclusionsOur data are consistent with an inverse association between Dietary Approach to Stop Hypertension diet score and incidence of CAD among US veterans.

Indexed as

Dietary Approaches To Stop HypertensionDiet, HealthyRisk Reduction BehaviorVeterans HealthAgedCoronary Artery DiseaseFemaleHumansIncidenceMaleMiddle AgedPatient CompliancePrognosisProspective StudiesProtective FactorsRisk Assessmentcoronary artery diseaseepidemiologynutrition

Identifiers

PMID29680824
PMCPMC6015298
OpenAlexW2799856498

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.