ArticleJournal of epidemiology and community health2018
Cross-sectional relationship between haemoglobin concentration and measures of physical and cognitive function in an older rural South African population.
Article in Journal of epidemiology and community health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Relationship Between Vitamin D Insufficiency and Anemia in Older Adults: An Approach Considering Clinical Aspects and Food Insecurity.Nutrients · 2024Article
- Relationship between hemoglobin and grip strength in older adults: the ActiFE study.Aging clinical and experimental research · 2024Article
- Sarcopenia and Anemia in Elderly Koreans: A Nationwide Population-Based Study.Healthcare (Basel, Switzerland) · 2023Article
- The association between anemia and depression in older adults and the role of treating anemia.Brain and behavior · 2023Article
- Causes of Moderate and Severe Anaemia in a High-HIV and TB-Prevalent Adult Population in the Eastern Cape Province, South Africa.International journal of environmental research and public health · 2023Article
- Relative Handgrip Strength Mediates the Relationship between Hemoglobin and Health-Related Quality of Life in Older Korean Adults.Healthcare (Basel, Switzerland) · 2022Article
- Relationship between Selected Functional Performance Parameters and the Occurrence of Anaemia in Hospitalized Females and Males Aged 80 and More.International journal of environmental research and public health · 2022Article
- Prevalence of Anemia and Factors Associated With Handgrip Strength in Indonesian Elderly Population.Cureus · 2022Article
- Higher hemoglobin levels are associated with better physical performance among older adults without anemia: a longitudinal analysis.BMC geriatrics · 2022Article
- Socioeconomic differences in handgrip strength and its association with measures of intrinsic capacity among older adults in six middle-income countries.Scientific reports · 2021Article
- Association between anemia, physical performance and cognitive function in Iranian elderly people: evidence from Bushehr Elderly Health (BEH) program.BMC geriatrics · 2021Article
- Red Cell Distribution Width and Dementia Among Rural-Dwelling Older Adults: The MIND-China Study.Journal of Alzheimer's disease : JAD · 2021Article
- Article
- Red Cell Distribution Width Is Directly Associated with Poor Cognitive Performance among Nonanemic, Middle-Aged, Urban Adults.The Journal of nutrition · 2020Article
- Association between Anemia and Cognitive Impairment among Elderly Patients with Heart Failure.International journal of environmental research and public health · 2019Article
- Patient blood management: A solution for South Africa.South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde · 2019Article
- Association of Anaemia and Depression: A Systematic Review and Meta-analysis.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
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Authors and funding
10 authors at 5 institutions in 5 countries.
Funding
Abstract
backgroundAge cohort differences in haemoglobin concentrations and associations with physical and cognitive performance among populations of lower income and middle-income countries have not previously been described. We examined the association between these factors among older men and women in rural South Africa.
methodsWe analysed cross-sectional data from a population-based study of rural South African men and women aged 40 and over (n=4499), with data drawn from questionnaire responses, a cognitive battery, objective physical function tests and blood tests. Anaemia was defined as a haemoglobin concentration <12 g/dL for women and <13 g/dL for men. We related haemoglobin concentrations to each of age, grip strength, walk speed and a latent cognitive function z-score for men and women separately. We used unadjusted correlations and linear models to adjust for comorbidities and inflammation.
resultsIn total, 1042 (43.0%) women and 833 (40.1%) men were anaemic. Haemoglobin concentrations were inversely correlated with age for men but not for women; in adjusted analyses, haemoglobin was 0.3 g/dL lower per decade older for men (95% CI 0.2 to 0.4 g/dL). In adjusted analyses, haemoglobin concentration was independently associated with grip strength in women (B=0.391, 95% CI 0.177 to 0.605), but this did not reach significance in men (B=0.266, 95% CI -0.019 to 0.552); no associations were observed between haemoglobin levels and walk speed or cognitive score.
conclusionsAnaemia was prevalent in this study population of middle-aged and older, rural South African adults, but in contrast to high-income countries, it was not associated with poor physical or cognitive function. Our findings need to be replicated in other populations.
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