Evidence map›Paper›PMID 29680480›Full record

ArticleUrology2018

The Receipt of Industry Payments is Associated With Prescribing Promoted Alpha-blockers and Overactive Bladder Medications.

Parth K Modi, Ye Wang, Peter S Kirk, James M Dupree, Eric A Singer, Steven L Chang

Abstract read
In one paragraph

Article in Urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Increasing Financial Payments From Industry to Medical Oncologists in the United States, 2014-2017.Journal of the National Comprehensive Cancer Network : JNCCN · 2021
    Article
  10. Observational
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Parth K ModiDepartment of Urology, Dow Division of Health Services Research, Michigan Medicine, Ann Arbor, MI. Electronic address: pamodi@med.umich.edu.
Ye WangDivision of Urology, Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA.
Peter S KirkDepartment of Urology, Dow Division of Health Services Research, Michigan Medicine, Ann Arbor, MI.
James M DupreeDepartment of Urology, Dow Division of Health Services Research, Michigan Medicine, Ann Arbor, MI.
Eric A SingerSection of Urologic Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ.
Steven L ChangDivision of Urology, Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA.

Funding

TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Tracie Saunders · 1997 to 2026
$94.5M
Advanced Training in Urologic OncologyT32CA180984 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Ganesh S Palapattu, VAHAKN B SHAHINIAN · 2014 to 2026
$3.4M
NCI NIH HHS P30 CA072720NCI NIH HHS T32 CA180984
6 · The paper itself

Abstract

objectiveTo determine the impact of physicians' financial relationships with the pharmaceutical industry on prescribing marketed alpha-blockers and overactive bladder (OAB) medications. We also aim to examine if the number or total value of transactions is influential. MATERIALS AND

methodsWe linked the Open Payments Program database of industry payments to prescribers with Medicare Part D prescription data. We used binomial logistic regression to identify the association between receipt of industry payment and prescribing of marketed alpha-blockers (silodosin) and OAB medications (fesoterodine, solifenacin, and mirabegron). We also evaluated the impact of increasing total value and number of payments on prescribing of marketed drugs.

resultsThe receipt of industry payment was associated with increased odds of prescribing the marketed drug for all included drugs: silodosin (odds ratio [OR] 34.1), fesoterodine (OR 5.9), solifenacin (OR 2.7), and mirabegron (OR 6.8) (all P <.001). We also found that increasing value of total payment and increasing frequency of payments were both independently associated with increased odds of prescribing with a dose-response effect.

conclusionThere is a consistent association between receipt of industry payment and prescribing marketed alpha-blockers and OAB medications. Both the total value and number of transactions were associated with prescribing.

Indexed as

AcetanilidesAdrenergic alpha-AntagonistsBenzhydryl CompoundsDatabases as TopicDrug IndustryDrug PrescriptionsHumansIndolesMedicare Part DPractice Patterns, Physicians'Solifenacin SuccinateThiazolesUnited StatesUrinary Bladder, OveractiveUrological AgentsUrologyAcetanilidesAdrenergic alpha-AntagonistsBenzhydryl CompoundsfesoterodineIndolesmirabegronsilodosinSolifenacin SuccinateThiazolesUrological Agents

Identifiers

PMID29680480
PMCPMC6005747

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.