Trial reportDrug and alcohol dependence2018
A multi-site proof-of-concept investigation of computerized approach-avoidance training in adolescent cannabis users.
Trial report in Drug and alcohol dependence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Approach With Caution: A Pilot Randomised Controlled Trial of Approach Bias Modification for People Undergoing Residential Treatment for Methamphetamine Use Disorder.Drug and alcohol review · 2026Trial
- Digital Intervention Components for Preventing and Reducing Substance Use in Adolescents and Emerging Adults: A Comprehensive Scoping Review.Journal of prevention (2022) · 2026Article
- Approach Bias Modification for reducing Co-Occurring Alcohol and cannabis use among treatment-seeking Adolescents: Protocol of a randomized controlled trial.Contemporary clinical trials communications · 2025Article
- Age of onset of nicotine use and severity of nicotine addiction symptoms are associated with hippocampal volume in late adolescents and emerging adults.Frontiers in adolescent medicine · 2025Article
- Substance Use and Social Influence as Risk Factors for Nicotine and Tobacco Product Use in Adolescents and Young Adults who use Electronic Nicotine Delivery Systems.Frontiers in adolescent medicine · 2025Article
- Assessing motivational biases in brain and behavior: Event-related potential and response time concomitants of the approach-avoidance task.Psychophysiology · 2024Article
- Investigating sex differences and age of onset in emotion regulation, executive functioning, and cannabis use in adolescents and young adults.Journal of cannabis research · 2024Article
- The effects of nicotine use during adolescence and young adulthood on gray matter cerebral blood flow estimates.Brain imaging and behavior · 2024Article
- Nicotine use during late adolescence and young adulthood is associated with changes in hippocampal volume and memory performance.Frontiers in neuroscience · 2024Article
- First Used Nicotine/Cannabis Product and Associated Outcomes in Late Adolescents.Substance use & misuse · 2024Article
- A cross-cultural fMRI investigation of cannabis approach bias in individuals with cannabis use disorder.Addictive behaviors reports · 2023Article
- Sadness-Based Approach-Avoidance Modification Training for Subjective Stress in Adults: Pilot Randomized Controlled Trial.JMIR formative research · 2023Article
- Approach avoidance training versus Sham in veterans with alcohol use disorder: protocol for a randomized controlled trial.BMC psychiatry · 2023Article
- Digital interventions for substance use disorders in young people: rapid review.Substance abuse treatment, prevention, and policy · 2023Review
- The Effects of Nicotine and Cannabis Co-Use During Late Adolescence on White Matter Fiber Tract Microstructure.Journal of studies on alcohol and drugs · 2022Article
- Preliminary Evidence for Cannabis and Nicotine Urinary Metabolites as Predictors of Verbal Memory Performance and Learning Among Young Adults.Journal of the International Neuropsychological Society : JINS · 2021Article
- The effects of nicotine and cannabis co-use during adolescence and young adulthood on white matter cerebral blood flow estimates.Psychopharmacology · 2020Article
- Proactive engagement of cognitive control modulates implicit approach-avoidance bias.Cognitive, affective & behavioral neuroscience · 2020Article
- Evidence Regarding Automatic Processing Computerized Tasks Designed For Health Interventions in Real-World Settings Among Adults: Systematic Scoping Review.Journal of medical Internet research · 2020Article
- Cannabis and the Developing Adolescent Brain.Current treatment options in psychiatry · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundFew effective treatment options exist for cannabis-using youth. This pilot study aimed to test Approach-Avoidance Training to reduce cannabis use with non-treatment-seeking adolescents.
methodsEighty cannabis-using non-treatment-seeking adolescents (average age 19) were recruited from San Diego, California and Charleston, South Carolina, and randomized to complete either six sessions of Cannabis Approach-Avoidance Task Training (CAAT-training) designed to reduce automatic approach biases for cannabis cues or CAAT-sham training. Change in two primary outcome variables was examined: 1) cannabis approach bias and 2) percent cannabis use days over study enrollment. Change in percent alcohol use days over study enrollment was explored as a secondary outcome.
resultsA mixed models repeated measures analysis confirmed the group by time interaction effect for approach bias failed to reach statistical significance (p = .06). Significant group by time interaction effects (ps < 0.05) predicted percent days of cannabis and alcohol use over study enrollment. Participants randomized to the avoid cannabis condition (CAAT-training) reported 7% fewer days of cannabis use compared to 0% change for sham; unexpectedly, those in the avoid cannabis condition reported 10% percent more alcohol use days compared to 3% more for sham.
conclusionsComputerized cognitive bias modification paradigms may have utility in reducing adolescent cannabis use. Future work should consider developing a paradigm that addresses both cannabis and alcohol, as well as alternative computerized approaches for coping with addictive behavior in conjunction with bias modification.
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