Evidence map›Paper›PMID 29679747›Full record

ArticleJournal of clinical epidemiology2018

Age, HIV status, and research context determined attrition in a longitudinal cohort in Nigeria.

Eileen O Dareng, Yinka Olaniyan, Sally N Adebamowo, Olabimpe R Eseyin, Michael K Odutola, Elonna M Obiefuna, Richard A Offiong, Paul P Pharoah, Clement A Adebamowo

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Eileen O DarengDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom; Office of Strategic Information, Research and Training, Institute of Human Virology, Abuja, Nigeria.
Yinka OlaniyanDepartment of Obstetrics and Gynecology, National Hospital, Abuja, Nigeria.
Sally N AdebamowoDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA; Marlene and Stewart Greenbaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA.
Olabimpe R EseyinOffice of Strategic Information, Research and Training, Institute of Human Virology, Abuja, Nigeria.
Michael K OdutolaOffice of Strategic Information, Research and Training, Institute of Human Virology, Abuja, Nigeria.
Elonna M ObiefunaOffice of Strategic Information, Research and Training, Institute of Human Virology, Abuja, Nigeria.
Richard A OffiongDepartment of Obstetrics and Gynecology, University of Abuja Teaching Hospital, Abuja, Nigeria.
Paul P PharoahDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
Clement A AdebamowoDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA; Marlene and Stewart Greenbaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: cadebamowo@som.umaryland.edu.
Institute of Human Virology · NGUniversity of Cambridge · GBNational Hospital Abuja · NGUniversity of Abuja Teaching Hospital · NGUniversity of Maryland, Baltimore · USUniversity of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center

Funding

African Collaborative Center for Microbiome and Genomics Research (ACCME)U54HG006947 · NHGRI · INSTITUTE OF HUMAN VIROLOGY · PI ADEBAMOWO, CLEMENT ADEBAYO · 2013 to 2018
$5.7M
Capacity Development for Research into AIDS Associated malignancies (CADRE)D43CA153792 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI ADEBAMOWO, CLEMENT ADEBAYO · 2010 to 2013
$1.8M
Cancer Research UK 10119Cancer Research UK 16561NCI NIH HHS D43 CA153792NHGRI NIH HHS U54 HG006947
6 · The paper itself

Abstract

objectivesWe explored determinants of attrition in a longitudinal cohort study in Nigeria. STUDY DESIGN AND

settingWe enrolled 1,020 women into a prospective study. Of these, 973 were eligible to return for follow-up. We investigated the determinants of attrition among eligible women using a sequential mixed methods design. We used logistic regression models to compare the baseline characteristics of responders and nonresponders. At the end of the parent study, we conducted four focus group discussions and eight key informant interviews with nonresponders.

resultsOf the 973 women included in the quantitative analysis, 26% were nonresponders. From quantitative analysis, older women were less likely to drop out than younger women (reference: women ≤30 years; OR 0.46; 95% confidence interval [CI] 0.30-0.70, P < 0.001 women 31-44 years; and OR 0.31; 95% CI 0.17-0.56, P < 0.001 women ≥45 years). HIV-positive women were also less likely to drop out of the study (OR 0.45; 95% CI 0.33-0.63, P < 0.001). From qualitative analysis, contextual factors that influenced attrition were high cost of participation, therapeutic misconceptions, inaccurate expectations, spousal disapproval, unpleasant side effects, challenges in maintaining contact with participants, and participant difficulties in locating the study clinic.

conclusionSeveral participant-, research-, and environment-related factors influence attrition. Retention strategies that address these barriers are important to minimize attrition.

Indexed as

AdultAge FactorsFemaleFocus GroupsHIV InfectionsHumansLongitudinal StudiesLost to Follow-UpMass ScreeningMiddle AgedNigeriaPatient ComplianceProspective StudiesQualitative ResearchResearch DesignAttritionDrop outLongitudinal studiesLoss to follow-upRetentionWithdrawal

Identifiers

PMID29679747
PMCPMC8015251
OpenAlexW2800599104

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.