Evidence map›Paper›PMID 29679508›Full record

ArticleMedical physics2018

Motion-compensated image reconstruction vs postreconstruction correction in respiratory-binned SPECT with standard and reduced-dose acquisitions.

Chao Song, Yongyi Yang, Wenyuan Qi, Miles N Wernick, P Hendrik Pretorius, Michael A King

Abstract readComparative Study
In one paragraph

Article in Medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Improving perfusion defect detection with respiratory motion correction in cardiac SPECT at standard and reduced doses.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chao SongMedical Imaging Research Center, Department of Electrical and Computer Engineering, Illinois Institute of Technology, Chicago, IL, 60616, USA.
Yongyi YangMedical Imaging Research Center, Department of Electrical and Computer Engineering, Illinois Institute of Technology, Chicago, IL, 60616, USA.
Wenyuan QiMedical Imaging Research Center, Department of Electrical and Computer Engineering, Illinois Institute of Technology, Chicago, IL, 60616, USA.
Miles N WernickMedical Imaging Research Center, Department of Electrical and Computer Engineering, Illinois Institute of Technology, Chicago, IL, 60616, USA.
P Hendrik PretoriusDepartment of Radiology, University of Massachusetts Medical School, Worcester, MA, 01655, USA.
Michael A KingDepartment of Radiology, University of Massachusetts Medical School, Worcester, MA, 01655, USA.

Funding

Probing Dose Limits in Cardiac SPECT with Reconstruction and Personalized ImagingR01HL122484 · NHLBI · ILLINOIS INSTITUTE OF TECHNOLOGY · PI KING, MICHAEL A, WERNICK, MILES N · 2014 to 2018
$3.9M
NHLBI NIH HHS R01 HL122484
6 · The paper itself

Abstract

purposeCardiac perfusion images in single-photon emission computed tomography (SPECT) can suffer from respiratory motion blur. We investigated a reconstruction approach for correcting respiratory motion in respiratory-binned acquisitions and assessed the benefit of this approach in both standard dose and reduced dose.

methodsWe modeled the acquired data from different respiratory bins by a joint probability distribution which was parameterized with respect to a common reference bin. The acquired data from all the respiratory bins were then utilized simultaneously for determining the source distribution in the reference bin using maximum a posteriori (MAP) estimation. We evaluated this approach with simulated imaging data and ten sets of clinical acquisitions, and compared it with a postreconstruction motion correction approach developed previously. We quantified the accuracy of the reconstruction results both at standard dose and with imaging dose reduced by 50% and 75%, respectively.

resultsThe proposed motion-compensated reconstruction (MCR) approach led to improved reconstruction of the myocardium in terms of both noise level and LV wall resolution. Compared to traditional acquisition (without motion correction), the proposed approach reduced the mean squared error of the image intensity in the myocardium by 27.59%, 20.59%, and 12.05% at full, half-, and quarter dose, respectively; the LV resolution, quantified by the full width at half-maximum (FWHM), was improved by 17.34%, 14.35%, and 12.95% at full, half-, and quarter dose, respectively; in addition, the proposed approach also improved the perfusion defect detectability at both full dose and reduced dose. Furthermore, with motion correction, the reconstruction results obtained at half-dose were comparable to that obtained at full dose without correction. Similar improvements were also demonstrated in the clinical acquisitions at different dose levels.

conclusionsRespiratory motion correction in perfusion SPECT can improve the reconstruction of the myocardium at both standard and reduced dose. At half-dose, the results obtained with motion correction are comparable to that of traditional reconstruction obtained at full dose. MCR can be more accurate than postreconstruction correction.

Indexed as

MovementRadiation DosageRespirationHeart VentriclesHumansImage Processing, Computer-AssistedReference StandardsTomography, Emission-Computed, Single-Photoncardiac SPECTmotion-compensated reconstructionrespiratory correction

Identifiers

PMID29679508
PMCPMC9559172

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.