Evidence map›Paper›PMID 29679338›Full record

ArticleObesity surgery2018

C-Reactive Protein on Postoperative Day 1: a Predictor of Early Intra-abdominal Infections After Bariatric Surgery.

Dino Kröll, Dominik Nakhostin, Guido Stirnimann, Suna Erdem, Tobias Haltmeier, Philipp Christoph Nett, Yves Michael Borbély

Abstract read
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Article in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dino KröllDepartment of Visceral Surgery and Medicine, Inselspital Bern, Bern University Hospital and University of Bern, Switzerland, 3010, Bern, Switzerland. dino.kroell@insel.ch.ORCID 0000-0001-8736-6619
Dominik NakhostinDepartment of Visceral Surgery and Medicine, Inselspital Bern, Bern University Hospital and University of Bern, Switzerland, 3010, Bern, Switzerland.
Guido StirnimannDepartment of Visceral Surgery and Medicine, Inselspital Bern, Bern University Hospital and University of Bern, Switzerland, 3010, Bern, Switzerland.
Suna ErdemDepartment of Visceral Surgery and Medicine, Inselspital Bern, Bern University Hospital and University of Bern, Switzerland, 3010, Bern, Switzerland.
Tobias HaltmeierDepartment of Visceral Surgery and Medicine, Inselspital Bern, Bern University Hospital and University of Bern, Switzerland, 3010, Bern, Switzerland.
Philipp Christoph NettDepartment of Visceral Surgery and Medicine, Inselspital Bern, Bern University Hospital and University of Bern, Switzerland, 3010, Bern, Switzerland.
Yves Michael BorbélyDepartment of Visceral Surgery and Medicine, Inselspital Bern, Bern University Hospital and University of Bern, Switzerland, 3010, Bern, Switzerland.
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly intra-abdominal infections (IAI) compromise short-term outcomes in bariatric surgery. The timely detection of IAI is challenging but essential to prevent major sequelae of such complications. C-reactive protein (CRP) is a reliable marker for detecting IAI after colorectal surgery. In bariatric surgery, data on CRP as a marker for IAI are limited, particularly for postoperative day one (POD1).

objectiveThe objective of this study was to assess CRP on POD1 as a predictor for early IAI (within 7 days following surgery) in patients after laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass (LRYGB).

methodsPatients with bariatric surgery between 08/2010 and 06/2017 were included. The predictive capacity of CRP for early IAI was determined using a receiver operating characteristics (ROC) analysis.

resultsIn 523 patients (68.5% female, LSG = 358, LRYGB = 165), 16 (3%) early IAI were observed. ROC analysis revealed a significant predictive capacity of POD1 CRP for early IAI, with a sensitivity and a specificity of 81.2 and 94.3%, respectively, at a CRP cut-off value of 70 mg/L. In patients with confirmed early IAI, 81.3% had a CRP level ≥ 70 mg/L (LSG 85.7%, LRYGB 77.8%). The negative predictive value for a CRP level < 70 mg/L was 99.4% overall and was 100 and 98% for LSG and LRYGB, respectively.

conclusionIn patients with a CRP level < 70 mg/L on POD1, early IAI can be excluded with high accuracy in bariatric patients. Thus, early postoperative CRP may be used to assess the risk of early IAI in enhanced recovery programs.

Indexed as

Intraabdominal InfectionsPostoperative ComplicationsBariatric SurgeryC-Reactive ProteinFemaleHumansMaleObesity, MorbidSensitivity and SpecificityC-Reactive ProteinC-reactive proteinIntra-abdominal infectionsOrgan space surgical site infectionsPostoperative complicationsROC curve analysisRoux-en-Y gastric bypassSleeve gastrectomy

Identifiers

PMID29679338
OpenAlexW2801427201

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.