Evidence map›Paper›PMID 29679284›Full record

ArticleCell stress & chaperones2018

Garlic (Allium sativum) exhibits a cardioprotective effect in experimental chronic renal failure rat model by reducing oxidative stress and controlling cardiac Na

Asmaa M S Gomaa, Alaa T Abdelhafez, Hazem A Aamer

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell stress & chaperones, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Asmaa M S GomaaDepartment of Medical Physiology, Faculty of Medicine, Assiut University, Assiut, 71515, Egypt. asmaagom3a@yahoo.com.
Alaa T AbdelhafezDepartment of Pharmacology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Hazem A AamerDepartment of Animal, Poultry and Environment Hygiene, Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt.
Assiut University · EGSohag University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gentamicin (GNT)-induced nephrotoxicity culminates into renal failure with a possible cardiovascular impact. Garlic extract (GE) is a cardiovascular protectant with limited mechanistic data. Therefore, we assessed the disturbance in specific cardiac parameters and the potential protective effect of GE supplementation against them in a rat model of GNT-induced chronic renal failure (CRF). Adult male rats (n = 24) were randomly assigned into four groups (n = 6 each): normal controls (CON), garlic extract controls (GE; 250 mg kg

Indexed as

GarlicPhytotherapyAnimalsAnti-Bacterial AgentsBlood PressureBody WeightCalciumCardiotonic AgentsCreatine Kinase, MB FormCreatinineDisease Models, AnimalGentamicinsHeartKidney Failure, ChronicL-Lactate DehydrogenaseMaleAnti-Bacterial AgentsCalciumCardiotonic AgentsCreatine Kinase, MB FormCreatinineGentamicinsL-Lactate DehydrogenasePlant ExtractsSodium-Potassium-Exchanging ATPaseCardiac parametersGarlic extractGentamicin-induced renal failureNa+/K+-ATPaseOxidative stress

Identifiers

PMID29679284
PMCPMC6111091
OpenAlexW2801811927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.