ArticleJournal of natural medicines2018
Changes in content of triterpenoids and polysaccharides in Ganoderma lingzhi at different growth stages.
Article in Journal of natural medicines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 44 citations in OpenAlex.
- Application of Metabolomics in the Exploration of Bioactive Compounds and Drug Development from Medicinal Fungi.Metabolites · 2026Review
- Integrated Transcriptomic and Metabolomic Analysis Reveals the Metabolic Basis and Regulatory Networks of Triterpenoid Biosynthesis inFoods (Basel, Switzerland) · 2026Article
- A Triterpenoid-Enriched GLE70 Fraction FromFood science & nutrition · 2026Article
- Effects of drying methods on the chemical composition and antioxidant activity ofFood chemistry: X · 2026Article
- Optimization of the Probiotic Fermentation Process ofFoods (Basel, Switzerland) · 2026Article
- Research Progress on the Regulation and Developmental Utilization of Bioactive Metabolites Synthesis inJournal of fungi (Basel, Switzerland) · 2025Review
- The Dichloromethane Fraction ofInternational journal of molecular sciences · 2025Article
- Structure-function insights of natural Ganoderma polysaccharides: advances in biosynthesis and functional food applications.Natural products and bioprospecting · 2025Review
- Evaluation of Two Different Treatments for Larch Logs as Substrates to CultivateLife (Basel, Switzerland) · 2024Article
- Ultrasound-assisted extraction of triterpenoids from Chaenomeles speciosa leaves: Process optimization, adsorptive enrichment, chemical profiling, and protection against ulcerative colitis.Ultrasonics sonochemistry · 2024Article
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- Changes of Active Substances inMolecules (Basel, Switzerland) · 2024Article
- Exploring Nutrient Profiles, Phytochemical Composition, and the Antiproliferative Activity ofFoods (Basel, Switzerland) · 2024Article
- Breeding a newFrontiers in microbiology · 2024Article
- Regulatory effect ofFrontiers in microbiology · 2024Review
- Mid-Infrared Spectroscopic Study of Cultivating Medicinal FungiJournal of fungi (Basel, Switzerland) · 2023Article
- Transcriptome and metabonomics combined analysis revealed the energy supply mechanism involved in fruiting body initiation in Chinese cordyceps.Scientific reports · 2023Article
- Investigation into Antiepileptic Effect of Ganoderic Acid A and Its Mechanism in Seizure Rats Induced by Pentylenetetrazole.BioMed research international · 2022Article
- Integrative Analysis of Selected Metabolites and the Fungal Transcriptome during the Developmental Cycle of Ganoderma lucidum Strain G0119 Correlates Lignocellulose Degradation with Carbohydrate and Triterpenoid Metabolism.Applied and environmental microbiology · 2021Article
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Authors and funding
12 authors at 5 institutions in 3 countries.
Funding
Abstract
Ganoderma lingzhi is a traditional medicinal mushroom, and its extract contains many bioactive compounds. Triterpenoids and polysaccharides are the primary bioactive components that contribute to its medicinal properties. In this study, we quantified 18 triterpenoids, total triterpenoid content and total polysaccharide content in the ethanol and water extracts of G. lingzhi at different growth stages. Triterpenoids were quantified by liquid chromatograph-tandem mass spectrometry in the multiple-reaction-monitoring mode. Total triterpenoid and total polysaccharide content were determined by colorimetric analysis. The results indicated that the fruit bodies at an early growth stage had a higher content of ganoderic acid A, C2, I and LM2, as well as of ganoderenic acid C and D, than those at a later growth stage. In contrast, ganoderic acid K, TN and T-Q contents were higher in mature fruit bodies (maturation stage). The highest total triterpenoid and total polysaccharide contents were found in fruit bodies before maturity (stipe elongation stage or early stage of pileus formation). Our results provide information which will contribute to the establishment of an efficient cultivation system for G. lingzhi with a higher content of triterpenoids.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.