Evidence map›Paper›PMID 29679257›Full record

ArticleJournal of thrombosis and thrombolysis2018

Anticoagulant-related nephropathy: a pathological note.

Vincenzo L'Imperio, Alessia Guarnieri, Federico Pieruzzi, Renato Alberto Sinico, Fabio Pagni

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Journal of thrombosis and thrombolysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Extracorporeal organ support and the kidney.Frontiers in nephrology · 2022
    Review
  5. Article
  6. Article
  7. Anticoagulant-Related Nephropathy: It's the Real McCoy.Clinical journal of the American Society of Nephrology : CJASN · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Vincenzo L'ImperioDepartment of Medicine and Surgery, Pathology, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy.
Alessia GuarnieriDepartment of Medicine and Surgery, Pathology, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy.
Federico PieruzziNephrology Unit, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Renato Alberto SinicoNephrology Unit, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Fabio PagniDepartment of Medicine and Surgery, Pathology, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy. fabio.pagni@unimib.it.
University of Milano-Bicocca · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The wide employment of oral anticoagulants and the introduction of new anticoagulant agents highlight disparate kind of toxicities that can affect many different organ systems. Renal toxicity by oral anticoagulants is a well-known entity characterized by hematuria and the worsening of renal function associated with uncontrolled INR values. Although it is mainly a clinical diagnosis, renal biopsy may help especially in challenging cases when multiple comorbidities and underlying renal conditions exist. The mechanism of the anticoagulant-induced damage is still debated and special tissue stains (such as Perls') could help in detecting the direct tubular toxicity induced by chronic glomerular bleeding. The employment of a diagnostic clinic-pathological flow-chart can help in the prompt detection and full characterization of these cases, improving the management of the patient.

Indexed as

AnticoagulantsHematuriaHumansInternational Normalized RatioRenal Insufficiency, ChronicAnticoagulantsAnticoagulant nephropathyPerls stainingWarfarin-related nephropathy

Identifiers

PMID29679257
OpenAlexW2799559075

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.