Evidence map›Paper›PMID 29679210›Full record

ArticleEuropean radiology2018

Gout of hand and wrist: the value of US as compared with DECT.

Andrea S Klauser, Ethan J Halpern, Sylvia Strobl, Mohamed M H Abd Ellah, Johann Gruber, Rosa Bellmann-Weiler, Thomas Auer, Gudrun Feuchtner, Werner Jaschke

Open access · hybridAbstract readComparative Study
In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Soft Tissue Masses of the Hand.Seminars in musculoskeletal radiology · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. [Clinical classification and treatment experience of wrist gouty arthritis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2021
    Article
  18. What Has Dual Energy CT Taught Us About Gout?Current rheumatology reports · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Andrea S KlauserRadiology Department, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Ethan J HalpernDepartment of Radiology and Urology, Jefferson Prostate Diagnostic and Kimmel Cancer Center, Thomas Jefferson University, 1025 Walnut Street, Suite 1112, Philadelphia, PA, 19107, USA.
Sylvia StroblRadiology Department, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria. Sylvia.Strobl@tirol-kliniken.at.
Mohamed M H Abd EllahRadiology Department, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Johann GruberDepartment of Internal Medicine II, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Rosa Bellmann-WeilerDepartment of Internal Medicine II, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Thomas AuerRadiology Department, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Gudrun FeuchtnerRadiology Department, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Werner JaschkeRadiology Department, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Innsbruck Medical University · ATThomas Jefferson University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe purpose of this study was to compare findings of ultrasound (US) with dual-energy CT (DECT) in patients presenting with suspected gouty hand and wrist arthritis.

methodsThis prospective study included 180 patients (136 men and 44 women, age range, 31- 94 years; mean age, 65.9 years) with an initial clinical diagnosis of acute gouty arthritis who underwent DECT and US examination. Intra- and extra-articular findings of each modality were tabulated and calculated with DECT as gold standard.

resultsThe final diagnosis of gout was positive in 97/180 patients (53.9%) by DECT, an alternative diagnosis confirmed in 83 patients. US showed a sensitivity of 70.1% (extra-articular: 42.5%, p < 0.0001; intra-articular: 80.3%, p = 0.14) and specificity of 51%. The double contour sign (DCS) was present in 58/61 patients with a positive US study for intra-articular gout (95.1%).

conclusionsSensitivity of US for diagnosis of gouty arthritis in hand and wrist is limited, particularly with respect to extra-articular urate deposition. The DCS is the most sensitive sign for the assessment of gouty hand and wrist arthritis by US. KEY POINTS: • Sensitivity of US for diagnosis of gouty arthritis in hand and wrist is limited, particularly with respect to extra-articular gouty deposits. • The double contour sign is the most sensitive finding for the assessment of gouty hand and wrist arthritis by US. • Although the sensitivity of US for diagnosis of gouty hand and wrist arthritis is limited, it can be used as a first-line imaging modality in the presence of the DCS.

Indexed as

AdultAgedAged, 80 and overFemaleGoutHandHumansMaleMiddle AgedProspective StudiesRadiography, Dual-Energy Scanned ProjectionSensitivity and SpecificityTomography, X-Ray ComputedUltrasonographyWristWrist JointArthritisgoutyHandTomographyUpper extremityWristx-ray computed

Identifiers

PMID29679210
PMCPMC6132720
OpenAlexW2799747520

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.