SynthesisCurrent neurology and neuroscience reports2018
Circulating Troponin I Level in Patients with Acute Ischemic Stroke.
Synthesis in Current neurology and neuroscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- Impact of high-sensitivity troponin elevation and dynamic changes on 90-day mortality in patients with acute ischemic stroke after mechanical thrombectomy: results from an observational cohort.Journal of neurointerventional surgery · 2023Observational
- Prevalence of myocardial injury in patients after acute ischaemic stroke according to standard criteria.European heart journal supplements : journal of the European Society of Cardiology · 2023Article
- Cardiac Troponin I and Risk of Stroke: A Mendelian Randomization Study.International journal of general medicine · 2022Article
- Elevated Cardiac Troponin Levels in Geriatric Patients Without ACS: Role of Comorbidities.CJC open · 2021Article
- Cerebral-Cardiac Syndrome and Diabetes: Cardiac Damage After Ischemic Stroke in Diabetic State.Frontiers in immunology · 2021Review
- The impact of cardiac troponin in elderly patients in the absence of acute coronary syndrome: A systematic review.International journal of cardiology. Heart & vasculature · 2020Review
- Article
- Turkish Society of Cardiology consensus paper on the rational use of cardiac troponins in daily practice.Anatolian journal of cardiology · 2019Article
- Acute ischemic stroke biomarkers: a new era with diagnostic promise?Acute medicine & surgeryReview
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
purpose of reviewCardiac troponin levels in the blood are an important biomarker of acute coronary events, but may also be elevated in the context of acute ischemic stroke without an obvious concurrent myocardial insult. The objective of this study and systematic review is to determine how high the circulating troponin I level can rise due to ischemic stroke. RECENT
findingsAnonymized medical records from Vanderbilt University Medical Center were reviewed identifying 151,972 unique acute ischemic stroke events, of which 1226 met criteria for inclusion in this study. Included patients had at least one measurement of troponin I level documented during the hospital visit when an acute ischemic stroke was diagnosed and were free of known cardiac/coronary disease, renal impairment, sepsis, or other confounders. In this group, 20.6% had a circulating troponin I level elevated over the reference range, but 99% were below 2.13 ng/mL. This is significantly lower than the distribution observed in a cohort of 89,423 unique cases of acute coronary syndrome (p < 2.2
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.