Evidence map›Paper›PMID 29679154›Full record

Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2018

Effectiveness of a mandibular advancement device in obstructive sleep apnea patients: a prospective clinical trial.

Rocío Marco Pitarch, Marina Selva García, Javier Puertas Cuesta, Jaime Marco Algarra, Enrique Fernández Julian, Antonio Fons Font

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. A consideration of factors affecting palliative oral appliance effectiveness for obstructive sleep apnea: a scoping review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  5. Article
  6. The effect of gradually increased mandibular advancement on the efficacy of an oral appliance in the treatment of obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Article
  7. Article
  8. Obstructive sleep apnea in adults.Dental press journal of orthodontics · 2019
    Review
  9. Article
4 · The record

Corrections and comments

  • Commented on by
    2018
5 · Who and what money

Authors and funding

6 authors.

Rocío Marco PitarchUnit of Prosthodontics and Occlusion, Stomatology Department, Faculty of Medicine and Dentistry, Universidad de Valencia, Calle Gasco Oliag 1, CP 46010, Valencia, Spain. rociomarco1@hotmail.com.ORCID http://orcid.org/0000-0002-8725-2969
Marina Selva GarcíaUnit of Prosthodontics and Occlusion, Stomatology Department, Faculty of Medicine and Dentistry, Universidad de Valencia, Calle Gasco Oliag 1, CP 46010, Valencia, Spain.
Javier Puertas CuestaSleep Unit, Neurophysiology Department, Hospital Universitario de La Ribera, Ctra. Corbera Km 1, Alzira, CP 46600, Valencia, Spain.
Jaime Marco AlgarraOtorhinolaryngology Department, Hospital Clínico Universitario, Avenida Blasco Ibañez 17, CP 46010, Valencia, Spain.
Enrique Fernández JulianOtorhinolaryngology Department, Hospital Clínico Universitario, Avenida Blasco Ibañez 17, CP 46010, Valencia, Spain.
Antonio Fons FontSection of Prosthodontics and Occlusion, Stomatology Department, Faculty of Medicine and Dentistry, Universidad de Valencia, Calle Gasco Oliag 1, CP 46010, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to determine the effectiveness of a mandibular advancement device in a sample of obstructive sleep apnea syndrome patients by the evaluation of respiratory and neurophysiologic parameters and clinical symptoms. Second, the influence of certain predictor factors related with the patient and the intraoral device, were considered in the final response with this treatment option.

methodsForty-one patients constituted the final sample. Outcomes were measured using polysomnography, Epworth sleepiness scale and an analogue visual snoring scale, before treatment and once the device was properly titrated.

resultsMean apnea-hypopnea index decreased from 22.5 ± 16.8 to 9.1 ± 11.6 (p ≤ 0.05), influencing only gender and Fujita index as predictor factors. The oxygen saturation, arousal index, percentages of sleep stages and sleep efficiency significantly improved with the mandibular advancement device (MAD) placement. The snoring index improved in absolute terms in 6.1 units and the excessive daytime sleepiness was reduced from 12.2 ± 4.7 to 8.5 ± 3.8 (p ≤ 0.00).

conclusionsThe successful treatment rate with the MAD was 65.8%. The placement and posterior regulation of the intraoral appliance efficiently reduced the apnea-hypopnea index, improved the sleep quality and the clinical symptomatology associated. Obstructive sleep apnea syndrome is a highly prevalent disease. and dentists should be aware of the benefits enhanced by this prosthetic device, considered the first treatment option by certain physicians.

Indexed as

AdultAgedFemaleHumansMaleMandibular AdvancementMiddle AgedPolysomnographyProspective StudiesSleep Apnea, ObstructiveSleep StagesSnoringTreatment OutcomeIntraoral deviceMandibular advancementObstructiveRespiratory sleep disorderSleep apnea

Identifiers

PMID29679154

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.