ReviewStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2018
Radiation-induced carotid artery lesions.
Review in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 68 citations in OpenAlex.
- Clinical and Surgical Outcome After Oncovascular Surgery of Soft Tissue and Osteogenic Sarcomas of the Limbs.Cancer reports (Hoboken, N.J.) · 2025Article
- Evaluation of ultrasonic energy for sealing 5-7 mm blood vessels in thoracoscopic surgery: a noninferiority randomized controlled trial.Translational lung cancer research · 2025Article
- The impact of different types of radiotherapy on cerebrovascular-specific death in patients with thyroid malignant tumors.Discover oncology · 2025Article
- Post-Radiotherapy Carotid Stenosis in a Patient With Head and Neck Cancer: A Case Report.Cureus · 2025Article
- Carotid artery stenosis and ischemic cerebrovascular events after radiotherapy in patients with head and neck cancer.PloS one · 2025Article
- Radiation Vasculopathy.Cerebrovascular diseases extra · 2025Review
- Risk factors of post-irradiation carotid blowout syndrome in patients with nasopharyngeal carcinoma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Carotid artery replacement with superficial femoral artery in a patient with recurrent radiation-induced carotid artery stenosis.Journal of vascular surgery cases and innovative techniques · 2024Article
- Article
- Progression rate of radiation-induced carotid stenosis in head and neck cancer survivors after statin treatment: a retrospective cohort study.Journal of neurology · 2024Article
- Management of intervenable factors to reduce vascular complications in patients with internal carotid artery occlusion treated by non-emergency endovascular treatment.Frontiers in neurology · 2024Article
- Comparison of Arterial Stiffness and Strain Measured with Speckle Tracking Carotid Strain Ultrasonography after Radiation and Surgical Treatment for Head and Neck Cancer-A Clinical Trial.Diagnostics (Basel, Switzerland) · 2023Article
- Identifying the Cause of Acute Left-Sided Visual Loss: A Clinical Dilemma.Journal of medical cases · 2023Article
- Review
- Radiation-induced oral mucositis presenting as atypical vascular proliferation: a case report.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2022Article
- Tissue Reactions and Mechanism in Cardiovascular Diseases Induced by Radiation.International journal of molecular sciences · 2022Review
- Ultrasound Evaluation of Carotid Artery Intima-Media Thickness: Effective Early Marker of Carotid Artery Disease in Adult Head and Neck Cancer Patients After Neck Radiation?Journal of the advanced practitioner in oncology · 2022Review
- Application of Carotid Duplex Ultrasonography in the Surveillance of Carotid Artery Stenosis after Neck Irradiation.Reviews in cardiovascular medicine · 2022Review
- Evaluation of Intima-Media Thickness and Arterial Stiffness as Early Ultrasound Biomarkers of Carotid Artery Atherosclerosis.Cardiology and therapy · 2022Review
- Outcomes of carotid artery stenting in patients with radiation arteritis compared with those with atherosclerotic disease.Journal of vascular surgery · 2022Article
Corrections and comments
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Authors and funding
14 authors at 12 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo review the current aspects of knowledge related to the risk of cerebrovascular events in patients receiving head and neck radiotherapy.
methodsA literature search was performed in PubMed. Papers meeting selection criteria were reviewed.
resultsWe provide an update on the problem by identifying key studies that have contributed to our current understanding of the epidemiology, radiologic features, pathogenesis, and treatment of the disease. The incidence of carotid artery stenosis ranged from 18 to 38% in patients who underwent radiotherapy for head and neck cancer versus from 0 to 9.2% among the nonirradiated patients. Neck irradiation increases the intima-media thickness of the carotid artery wall. These changes are the earliest visible alteration in the carotid wall and are also detected with color Doppler ultrasonography. Endovascular treatment with a carotid angioplasty and stenting is the first-line treatment for most symptomatic patients.
conclusionsRadiation-induced atherosclerosis is a different and accelerated form of atherosclerosis, which implies a more aggressive disease with a different biologic behavior. The disease is characterized by a high rate of carotid artery stenosis compared to those observed in nonirradiated control group patients. To prevent the risk of stroke, surveillance and imaging with ultrasonography should enable detection of severe stenosis. Endovascular treatment with a carotid angioplasty and stenting has been proposed as an attractive and minimally invasive alternative for some radiation-induced stenoses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.