ArticleBMJ open2018
Prescribing and deprescribing antihypertensive medication in older people by Dutch general practitioners: a qualitative study.
Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Barriers and facilitators to deprescribing of cardiovascular medications: a systematic review.BMJ open · 2022Pooled it
- Pharmacist-led deprescribing of cardiovascular and diabetes medication within a clinical medication review: the LeMON study (Less Medicines in Older Patients in the Netherlands), a cluster randomized controlled trial.International journal of clinical pharmacy · 2025Trial
- Efficacy and Safety of Dapagliflozin in Patients With Chronic Kidney Disease Across the Spectrum of Frailty.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Trial
- Effects of Antihypertensive Deprescribing Strategies on Blood Pressure, Adverse Events, and Orthostatic Symptoms in Older Adults: Results From TONE.American journal of hypertension · 2022Trial
- Hypertension management in the oldest-old: a survey of physicians in Swedish primary health care.Scandinavian journal of primary health care · 2026Article
- Efficacy and safety of antihypertensive drugs deprescribing in older adults: A systematic review and meta-analysis of randomized controlled trials.International journal of cardiology. Cardiovascular risk and prevention · 2026Review
- General practitioners' perspectives, preferences, and practices in prescribing antihypertensive medication in primary, uncomplicated hypertension.Family practice · 2025Article
- Primary care physicians' perceptions of hypertension management in Qatar: A qualitative study using the theoretical domains framework.PloS one · 2025Article
- Strategies for Identifying Patients for Deprescribing of Blood Pressure Medications in Routine Practice: An Evidence Review.Current hypertension reports · 2024Review
- Perspectives of general practitioners and memory clinic patients on ageing and cognitive decline to inform the design of a decentralised antihypertensive dementia prevention trial.Cerebral circulation - cognition and behavior · 2024Article
- Older Adult Perspectives on Statin Continuation and Discontinuation in Primary Cardiovascular Disease Prevention: A Mixed-Methods Study.Patient preference and adherence · 2024Article
- How general practitioners perceive the aging trajectory of oldest-old - A qualitative study.BMC primary care · 2023Article
- Deprescribing Medications that Increase the Risk of Falls in Older People: Exploring Doctors' Perspectives Using the Theoretical Domains Framework (TDF).Drugs & aging · 2022Article
- Hypertension treatment in the oldest-old: focus group interviews with Swedish general practitioners.Scandinavian journal of primary health care · 2022Article
- Deprescribing medicines in older people living with multimorbidity and polypharmacy: the TAILOR evidence synthesis.Health technology assessment (Winchester, England) · 2022Review
- Article
- GPs' mindlines on deprescribing antihypertensives in older patients with multimorbidity: a qualitative study in English general practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Article
- Rates, determinants and success of implementing deprescribing in people with type 2 diabetes: A scoping review.Diabetic medicine : a journal of the British Diabetic Association · 2021Article
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Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo explore general practitioners' (GPs) routines and considerations on (de)prescribing antihypertensive medication (AHM) in older patients, their judgement on usability of the current guideline and needs for future support.
designSemistructured interviews.
settingDutch general practice.
participantsFifteen GPs were purposively sampled based on level of experience and practice characteristics until saturation was reached.
resultsGPs appeared reluctant to start AHM, especially in patient >80 years. High systolic blood pressure and history of cardiovascular disease or diabetes were enablers to start or intensify treatment. Reasons to refrain from this were frailty and patient preference. GPs described a tendency to continue AHM regimens unchanged, influenced by daily time constraints, automated prescription routines and anticipating discomfort when disturbing patients' delicate balance. GPs were only inclined to deprescribe AHM in terminally ill patients or after prolonged achievement of target levels in combination with side effects or patient preference. Deprescription was facilitated when GPs had experience with patients showing increased quality of life after deprescription and was withheld by anticipated regret (ie, GPs' fear of a stroke after deprescribing). GPs felt insufficient guidance from current guidelines, especially on deprescription.
conclusionsGPs are reluctant to start or deprescribe AHM in older people and have a propensity to continue AHM within a daily routine that insufficiently supports critical medication review. (De)prescription is influenced by patient preferences and anticipated regret and current guidelines provide insufficient guidance.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.