Evidence map›Paper›PMID 29678899›Full record

ArticleBioscience reports2018

ZFAS1 functions as an oncogenic long non-coding RNA in bladder cancer.

Haifan Yang, Ge Li, Bo Cheng, Rui Jiang

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. An Overview of Angiogenesis in Bladder Cancer.Current oncology reports · 2023
    Review
  5. Article
  6. Article
  7. Study on the Role and Mechanism of LncRNA ZFasL in Renal Carcinoma.Computational intelligence and neuroscience · 2022
    Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Higher Expression of Linc00152 Promotes Bladder Cancer Proliferation and Metastasis by Activating the Wnt/β-Catenin Signaling Pathway.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Haifan YangDepartment of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China.
Ge LiDepartment of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China.
Bo ChengDepartment of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China.
Rui JiangDepartment of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China jiangrui_lz@126.com.
Affiliated Hospital of Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNA (lncRNA) ZFAS1 (zinc finger antisense 1) has been suggested to have an oncogenic role in the tumorigenesis of human malignant tumors. However, the expression status and biological function of ZFAS1 in bladder cancer is still unknown. Thus, the purpose of the present study is to explore the clinical value of ZFAS1 in bladder cancer patients, and the biological function of ZFAS1 in bladder cancer cell. In the present study, we found ZFAS1 expression was increased in bladder cancer tissues compared with paired adjacent normal tissues through analyzing the Cancer Genome Atlas (TCGA) database. Furthermore, we confirmed that levels of ZFAS1 expression were elevated in bladder cancer tissues and cell lines compared with normal bladder tissues and normal uroepithelium cell line, respectively. Then, we observed that the expression level of ZFAS1 was positively associated with clinical stag, muscularis invasion, lymph node metastasis, and distant metastasis in bladder cancer patients. The experiments

Indexed as

Adaptor Proteins, Signal TransducingCalcium-Binding ProteinsCarcinogenesisCarrier ProteinsCell Line, TumorCell MovementCell ProliferationEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansKruppel-Like Transcription FactorsLymphatic MetastasisNeoplasm InvasivenessRNA, Long NoncodingUrinary Bladder NeoplasmsZinc Finger E-box-Binding Homeobox 1Adaptor Proteins, Signal TransducingCalcium-Binding ProteinsCarrier ProteinsKLF2 protein, humanKruppel-Like Transcription FactorsNKD2 protein, humanRNA, Long NoncodingZEB1 protein, humanZEB2 protein, humanZFAS1 long non-coding RNA, humanZinc Finger E-box-Binding Homeobox 1Zinc Finger E-box Binding Homeobox 2biomarkerbladder cancerlncRNAZFAS1

Identifiers

PMID29678899
PMCPMC6048211
OpenAlexW2802311426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.