Evidence map›Paper›PMID 29678540›Full record

ArticleMagnetic resonance imaging2018

Quantitative diffusion MRI using reduced field-of-view and multi-shot acquisition techniques: Validation in phantoms and prostate imaging.

Yuxin Zhang, James Holmes, Iñaki Rabanillo, Arnaud Guidon, Shane Wells, Diego Hernando

Abstract readEvaluation Study
In one paragraph

Article in Magnetic resonance imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. High-resolution Diffusion-weighted Imaging of the Prostate Using Multiplexed Sensitivity-encoding: Comparison with the Conventional and Reduced Field-of-view Techniques.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yuxin ZhangDepartment of Medical Physics, University of Wisconsin Madison, Madison, WI, United States; Department of Radiology, School of Medicine and Public Health, University of Wisconsin Madison, Madison, WI, United States.
James HolmesDepartment of Radiology, School of Medicine and Public Health, University of Wisconsin Madison, Madison, WI, United States.
Iñaki RabanilloLaboratorio MR de Procesado de Imagen, Universidad de Valladolid, Valladolid, Spain.
Arnaud GuidonApplications and Workflow, GE Healthcare, Boston, MA, United States.
Shane WellsDepartment of Radiology, School of Medicine and Public Health, University of Wisconsin Madison, Madison, WI, United States.
Diego HernandoDepartment of Medical Physics, University of Wisconsin Madison, Madison, WI, United States; Department of Radiology, School of Medicine and Public Health, University of Wisconsin Madison, Madison, WI, United States. Electronic address: dhernando@wisc.edu.
University of Wisconsin–Madison · USUniversidad de Valladolid · ES

Funding

Wisconsin Multidisciplinary K12 Urologic Research Career Development ProgramK12DK100022 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI CHAD M. VEZINA · 2013 to 2026
$8.6M
NIDDK NIH HHS K12 DK100022
6 · The paper itself

Abstract

purposeTo evaluate the reproducibility of quantitative diffusion measurements obtained with reduced Field of View (rFOV) and Multi-shot EPI (msEPI) acquisitions, using single-shot EPI (ssEPI) as a reference.

methodsDiffusion phantom experiments, and prostate diffusion-weighted imaging in healthy volunteers and patients with known or suspected prostate cancer were performed across the three different sequences. Quantitative diffusion measurements of apparent diffusion coefficient, and diffusion kurtosis parameters (healthy volunteers), were obtained and compared across diffusion sequences (rFOV, msEPI, and ssEPI). Other possible confounding factors like b-value combinations and acquisition parameters were also investigated.

resultsBoth msEPI and rFOV have shown reproducible quantitative diffusion measurements relative to ssEPI; no significant difference in ADC was observed across pulse sequences in the standard diffusion phantom (p = 0.156), healthy volunteers (p ≥ 0.12) or patients (p ≥ 0.26). The ADC values within the non-cancerous central gland and peripheral zone of patients were 1.29 ± 0.17 × 10

conclusionBoth rFOV and msEPI have the potential to provide high image quality with reproducible quantitative diffusion measurements in prostate diffusion MRI.

Indexed as

AdultAgedDiffusion Magnetic Resonance ImagingEcho-Planar ImagingEvaluation Studies as TopicHumansImage Interpretation, Computer-AssistedMaleMiddle AgedPhantoms, ImagingProstateReproducibility of ResultsMulti-shot EPIProstate imagingQuantitative diffusion MRIReduced field-of-view

Identifiers

PMID29678540
PMCPMC6015549
OpenAlexW2800394185

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.