Evidence map›Paper›PMID 29678311›Full record

ArticleAnnals of epidemiology2018

Neighborhood disadvantage and racial disparities in colorectal cancer incidence: a population-based study in Louisiana.

Denise M Danos, Tekeda F Ferguson, Neal R Simonsen, Claudia Leonardi, Qingzhao Yu, Xiao-Cheng Wu, Richard A Scribner

Abstract read
In one paragraph

Article in Annals of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  4. Area-Level Determinants in Colorectal Cancer Spatial Clustering Studies: A Systematic Review.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Denise M DanosStanley S. Scott Cancer Center, Louisiana State University Health-New Orleans, School of Medicine, New Orleans, LA.
Tekeda F FergusonStanley S. Scott Cancer Center, Louisiana State University Health-New Orleans, School of Medicine, New Orleans, LA; Department of Epidemiology, Louisiana State University Health-New Orleans, School of Public Health, New Orleans, LA. Electronic address: tferg4@lsuhsc.edu.
Neal R SimonsenStanley S. Scott Cancer Center, Louisiana State University Health-New Orleans, School of Medicine, New Orleans, LA.
Claudia LeonardiStanley S. Scott Cancer Center, Louisiana State University Health-New Orleans, School of Medicine, New Orleans, LA; Department of Community and Behavioral Health, Louisiana State University Health-New Orleans, School of Public Health, New Orleans, LA.
Qingzhao YuStanley S. Scott Cancer Center, Louisiana State University Health-New Orleans, School of Medicine, New Orleans, LA; Department of Biostatistics, Louisiana State University Health-New Orleans, School of Public Health, New Orleans, LA.
Xiao-Cheng WuDepartment of Epidemiology, Louisiana State University Health-New Orleans, School of Public Health, New Orleans, LA; Louisiana Tumor Registry, Louisiana State University Health-New Orleans, School of Public Health, New Orleans, LA.
Richard A ScribnerStanley S. Scott Cancer Center, Louisiana State University Health-New Orleans, School of Medicine, New Orleans, LA; Department of Epidemiology, Louisiana State University Health-New Orleans, School of Public Health, New Orleans, LA.

Funding

Molecular and Soc. Determinants of Obesity and Metabolic Disorders in YouthU54MD008176 · NIMHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FOUAD, MONA N. · 2012 to 2016
$13.7M
Trends of disparities in breast cancer progression and health care considering multilevel risk factorsR15MD012387 · NIMHD · LSU HEALTH SCIENCES CENTER · PI YU, QINGZHAO · 2017 to 2023
$1.1M
Community-Academic Partnership to Address Health Dispairties in New OrleansR24MD008121 · NIMHD · LSU HEALTH SCIENCES CENTER · PI SCRIBNER, RICHARD ALLEN · 2013 to 2015
$947k
NIMHD NIH HHS R15 MD012387NIMHD NIH HHS R24 MD008121NIMHD NIH HHS U54 MD008176
6 · The paper itself

Abstract

purposeColorectal cancer (CRC) continues to demonstrate racial disparities in incidence and survival in the United States. This study investigates the role of neighborhood concentrated disadvantage in racial disparities in CRC incidence in Louisiana.

methodsLouisiana Tumor Registry and U.S. Census data were used to assess the incidence of CRC diagnosed in individuals 35 years and older between 2008 and 2012. Neighborhood concentrated disadvantage index (CDI) was calculated based on the PhenX Toolkit protocol. The incidence of CRC was modeled using multilevel binomial regression with individuals nested within neighborhoods.

resultsOur study included 10,198 cases of CRC. Adjusting for age and sex, CRC risk was 28% higher for blacks than whites (risk ratio [RR] = 1.28; 95% confidence interval [CI] = 1.22-1.33). One SD increase in CDI was associated with 14% increase in risk for whites (RR = 1.14; 95% CI = 1.10-1.18) and 5% increase for blacks (RR = 1.05; 95% CI = 1.02-1.09). After controlling for differential effects of CDI by race, racial disparities were not observed in disadvantaged areas.

conclusionCRC incidence increased with neighborhood disadvantage and racial disparities diminished with mounting disadvantage. Our results suggest additional dimensions to racial disparities in CRC outside of neighborhood disadvantage that warrants further research.

Indexed as

Health Status DisparitiesResidence CharacteristicsSocial Determinants of HealthAdultAgedColorectal NeoplasmsFemaleHealthcare DisparitiesHumansIncidenceLouisianaMaleMiddle AgedSocioeconomic FactorsColorectal cancerConcentrated disadvantageDisparitiesMultilevel modelingSocial epidemiology

Identifiers

PMID29678311
PMCPMC6138869

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.