ArticleTrials2018
Treating prolonged grief disorder with prolonged grief-specific cognitive behavioral therapy: study protocol for a randomized controlled trial.
Article in Trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Suicidal incidence and gender-based discrepancies in prolonged grief disorder: insights from a meta-analysis and systematic review.Frontiers in psychiatry · 2024Pooled it
- Present-centered therapy (PCT) for post-traumatic stress disorder (PTSD) in adults.The Cochrane database of systematic reviews · 2019Pooled it
- Development and validation of the Aarhus Structured Clinical Interview for Prolonged Grief Disorder in ICD-11 and DSM-5-TR (A-PGDi).European journal of psychotraumatology · 2025Article
- Mindfulness and Relaxation Interventions Reduce Depression, Negative Affect and Stress in Widow(er)s.Journal of loss & trauma · 2025Article
- Symptoms and levels of ICD-11 Prolonged Grief Disorder in a representative community sample of UK adults.Social psychiatry and psychiatric epidemiology · 2023Article
- Introduction and evaluation of a therapeutic adherence and competence scale for grief-focused cognitive behavioural therapy.European journal of psychotraumatology · 2022Article
- Predictors of Prolonged Grief Disorder in a German Representative Population Sample: Unexpectedness of Bereavement Contributes to Grief Severity and Prolonged Grief Disorder.Frontiers in psychiatry · 2022Article
- Mental Imagery in Patients with Prolonged Grief Disorder: a Comparison with Matched Bereaved Healthy Controls.The Psychiatric quarterly · 2021Article
- Prolonged Grief Disorder: Course, Diagnosis, Assessment, and Treatment.Focus (American Psychiatric Publishing) · 2021Review
- Narrative reconstruction therapy for prolonged grief disorder - a pilot study.European journal of psychotraumatology · 2021Article
- Review of Grief Therapies for Older Adults.Current geriatrics reports · 2021Review
- Feasibility of Present-Centered Therapy for Prolonged Grief Disorder: Results of a Pilot Study.Frontiers in psychiatry · 2021Article
- When does grief become pathological? Evaluation of the ICD-11 diagnostic proposal for prolonged grief in a treatment-seeking sample.European journal of psychotraumatology · 2020Article
- Commentary on evidence in support of a grief-related condition as a DSM diagnosis.Depression and anxiety · 2020Review
- Traumatic grief research and care in the aftermath of the COVID-19 pandemic.European journal of psychotraumatologyArticle
- The Grieving Heart: The Association Between Hemodynamic Responses to Grief Recall and Prolonged Grief Disorder Symptoms.Biopsychosocial science and medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundProlonged grief disorder (PGD) has emerged as a well-defined and relatively common mental disorder that will be included in the upcoming revision of the International Classification of Diseases. Recent trials with grief-specific, mostly cognitive behavioral interventions for patients with a clinically relevant diagnosis of PGD showed large effect sizes. However, a small trial suggested that non-specific behavioral activation might suffice to improve PGD. So, more evidence for the relative efficacy of grief-specific treatments is needed, as is more research on the predictors of treatment success. The purpose of the proposed trial is to evaluate a newly developed and successfully pilot-tested, prolonged grief-specific, integrative cognitive behavioral therapy (PG-CBT) compared to an active yet unspecific treatment, present-centered therapy (PCT).
methodsIn a multicenter, randomized controlled trial with 204 adults with a primary diagnosis of PGD, PG-CBT is compared to PCT, assuming the superiority of PG-CBT. Both treatments consist of 20 to 24 individual sessions, with an overall treatment length of about 6 months. The primary outcome, grief symptom severity, is assessed by blinded interviewers 12 months after randomization. Secondary outcomes are grief symptom severity at post treatment, in addition to self-reported overall mental health symptoms, depressive and somatoform symptoms at post treatment and 12 months post randomization. Possible moderators and mediators of treatment success are also explored. DISCUSSION: The trial is designed to avoid bias as much as possible (stratified randomization performed independently, blinded outcome assessment, intention-to-treat-analysis, balanced treatment dose, continuous supervision, control for allegiance effects) thereby enhancing internal validity. At the same time, some aspects of the trial will ensure clinical relevance (recruiting at outpatient clinics that are part of routine health care and keeping exclusion criteria to a minimum). Since the trial is powered adequately for the primary outcome, all secondary analyses including moderator analyses are exploratory by nature. The results will extend the knowledge on efficacious treatment of PGD and its predictors.
trial registrationGerman Clinical Trials Register, ID: DRKS00012317 . Registered on 6 September 2017.
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