Evidence map›Paper›PMID 29677489›Full record

ArticleMolecular cell2018

Transvection Goes Live-Visualizing Enhancer-Promoter Communication between Chromosomes.

Albert Tsai, Robert H Singer, Justin Crocker

Abstract readComment
PubMed Publisher
In one paragraph

Article in Molecular cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Albert TsaiDevelopmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Robert H SingerDepartment of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York, USA; Janelia Research Campus of the HHMI, Ashburn, Virginia, USA.
Justin CrockerDevelopmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany. Electronic address: justin.crocker@embl.de.

Funding

Tools For Imaging the Functional Genome in Living Cells and TissuesU01EB021236 · NIBIB · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI DARZACQ, XAVIER, SINGER, ROBERT H · 2015 to 2017
$2.5M
Howard Hughes Medical InstituteNIBIB NIH HHS U01 EB021236
6 · The paper itself

Abstract

Lim et al. (2018) use live imaging in Drosophila embryos to show that enhancers can drive transcription from promoters on another chromosome when they are in close proximity. In addition, they show that multiple promoters can access the same enhancer without competition, potentially sharing a pool of factors in a transcriptional "hub."

Indexed as

Enhancer Elements, GeneticAnimalsChromosomesDrosophilaDrosophila ProteinsPromoter Regions, GeneticDrosophila Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.