Evidence map›Paper›PMID 29677164›Full record

Trial reportNutrients2018

The Mediating Role of Overweight and Obesity in the Prospective Association between Overall Dietary Quality and Healthy Aging.

Karen E Assmann, Indunil Ruhunuhewa, Moufidath Adjibade, Zhen Li, Raphaëlle Varraso, Serge Hercberg, Pilar Galan, Emmanuelle Kesse-Guyot

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Clarifying healthy aging: building a common language for policy innovation within the Age-It Research Program.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. The Role of Nutritional Factors in Asthma: Challenges and Opportunities for Epidemiological Research.International journal of environmental research and public health · 2021
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karen E AssmannNutritional Epidemiology Research Team (EREN), Centre of Research in Epidemiology and Statistics Sorbonne Paris Cité, Inserm (U1153), Inra (U1125), Cnam, Paris 13 University, COMUE Sorbonne Paris Cité, 93017 Bobigny, France. k.assmann@eren.smbh.univ-paris13.fr.
Indunil RuhunuhewaNutritional Epidemiology Research Team (EREN), Centre of Research in Epidemiology and Statistics Sorbonne Paris Cité, Inserm (U1153), Inra (U1125), Cnam, Paris 13 University, COMUE Sorbonne Paris Cité, 93017 Bobigny, France. indunil_ruhunuhewa@yahoo.com.
Moufidath AdjibadeNutritional Epidemiology Research Team (EREN), Centre of Research in Epidemiology and Statistics Sorbonne Paris Cité, Inserm (U1153), Inra (U1125), Cnam, Paris 13 University, COMUE Sorbonne Paris Cité, 93017 Bobigny, France. m.adjibade@eren.smbh.univ-paris13.fr.
Zhen LiINSERM, U1168, VIMA: Aging and Chronic Diseases, Epidemiological and Public Health Approaches, F-94807 Villejuif, France. lizhen1986@scu.edu.cn.
Raphaëlle VarrasoINSERM, U1168, VIMA: Aging and Chronic Diseases, Epidemiological and Public Health Approaches, F-94807 Villejuif, France. raphaelle.varraso@inserm.fr.
Serge HercbergNutritional Epidemiology Research Team (EREN), Centre of Research in Epidemiology and Statistics Sorbonne Paris Cité, Inserm (U1153), Inra (U1125), Cnam, Paris 13 University, COMUE Sorbonne Paris Cité, 93017 Bobigny, France. s.hercberg@eren.smbh.univ-paris13.fr.
Pilar GalanNutritional Epidemiology Research Team (EREN), Centre of Research in Epidemiology and Statistics Sorbonne Paris Cité, Inserm (U1153), Inra (U1125), Cnam, Paris 13 University, COMUE Sorbonne Paris Cité, 93017 Bobigny, France. k.assmann@eren.smbh.univ-paris13.fr.
Emmanuelle Kesse-GuyotNutritional Epidemiology Research Team (EREN), Centre of Research in Epidemiology and Statistics Sorbonne Paris Cité, Inserm (U1153), Inra (U1125), Cnam, Paris 13 University, COMUE Sorbonne Paris Cité, 93017 Bobigny, France. e.kesse@eren.smbh.univ-paris13.fr.ORCID 0000-0002-9715-3534

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur objective was to quantify to what extent the association between adherence to the French nutritional recommendations at midlife, measured by the Programme National Nutrition Santé-Guideline Score (PNNS-GS), and healthy aging (HA) is mediated by body mass index (BMI) status.

methodsWe analyzed data from 2249 participants of the French 'Supplementation with Vitamins and Mineral Antioxidants' (SU.VI.MAX-'SUpplémentation en VItamines et Minéraux AntioXydants') cohort. At baseline (1994⁻1995), data on BMI status (<25 vs. ≥25 and <30 vs. ≥30) and diet were collected. At follow-up (2007⁻2009), HA status (yes/no) was evaluated via a multidimensional concept focusing on chronic disease incidence, physical and cognitive functioning, mental and social health, pain, and perceived health. Relative risks (RR) were estimated by extensively adjusted robust-error-variance Poisson regression, and counterfactual-based mediation analysis was performed.

resultsOur HA criteria were met by 39% of participants. We identified a positive direct relation of a greater adherence to the French nutritional recommendations, with the probability of HA (RR

conclusionThese results indicate that high dietary quality may contribute to the preservation of overall health during aging, partly via obesity prevention and partly via other mechanisms.

Indexed as

Diet, HealthyHealthy AgingNutritional StatusNutritive ValueObesityAge FactorsBody Mass IndexChi-Square DistributionDietary SupplementsDouble-Blind MethodFemaleFranceHumansLogistic ModelsMaleMiddle Agedagingbody mass index (BMI)dietnutritionoverweight obesityprevention

Identifiers

PMID29677164
PMCPMC5946300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.