ArticleHuman brain mapping2018
Core networks and their reconfiguration patterns across cognitive loads.
Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Overlapping and dissociable brain activations for fluid intelligence and executive functions.Cognitive, affective & behavioral neuroscience · 2021Pooled it
- Connectivity differences between Gulf War Illness (GWI) phenotypes during a test of attention.PloS one · 2019Trial
- Integrated brain and body mechanisms underlying acute stress and trauma-related vulnerability.Neurobiology of stress · 2026Article
- Article
- Flexible Reconfigurations of Brain Networks During Decisions With Predefined Versus Self-Generated Options.Human brain mapping · 2025Article
- Reconfiguration of Functional Brain Network Organization and Dynamics With Changing Cognitive Demands in Children With Attention-Deficit/Hyperactivity Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Task-Rest Reconfiguration Efficiency of the Reward Network Across Adolescence and Its Association With Early Life Stress and Depressive Symptoms.Journal of the American Academy of Child and Adolescent Psychiatry · 2025Article
- Differential spatial working memory-related functional network reconfiguration in young and older adults.Network neuroscience (Cambridge, Mass.) · 2024Article
- Mindfulness-based therapy improves brain functional network reconfiguration efficiency.Translational psychiatry · 2023Article
- Interaction Between Memory Load and Experimental Design on Brain Connectivity and Network Topology.Neuroscience bulletin · 2023Article
- Static and dynamic functional connectome reveals reconfiguration profiles of whole-brain network across cognitive states.Network neuroscience (Cambridge, Mass.) · 2023Article
- Impaired time-distance reconfiguration patterns in Alzheimer's disease: a dynamic functional connectivity study with 809 individuals from 7 sites.BMC bioinformatics · 2022Article
- Shared and unique brain network features predict cognitive, personality, and mental health scores in the ABCD study.Nature communications · 2022Article
- A survey of brain network analysis by electroencephalographic signals.Cognitive neurodynamics · 2022Article
- Abnormal Large-Scale Neuronal Network in High Myopia.Frontiers in human neuroscience · 2022Article
- Impaired body-centred sensorimotor transformations in congenitally deaf people.Brain communications · 2022Article
- Physical activity is associated with increased resting-state functional connectivity in networks predictive of cognitive decline in clinically unimpaired older adults.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- Efficient Brain Connectivity Reconfiguration Predicts Higher Marital Quality and Lower Depression.Social cognitive and affective neuroscience · 2021Article
- Task-related brain functional network reconfigurations relate to motor recovery in chronic subcortical stroke.Scientific reports · 2021Article
- Age differences in functional network reconfiguration with working memory training.Human brain mapping · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Different cognitively demanding tasks recruit globally distributed but functionally specific networks. However, the configuration of core networks and their reconfiguration patterns across cognitive loads remain unclear, as does whether these patterns are indicators for the performance of cognitive tasks. In this study, we analyzed functional magnetic resonance imaging data of a large cohort of 448 subjects, acquired with the brain at resting state and executing N-back working memory (WM) tasks. We discriminated core networks by functional interaction strength and connection flexibility. Results demonstrated that the frontoparietal network (FPN) and default mode network (DMN) were core networks, but each exhibited different patterns across cognitive loads. The FPN and DMN both showed strengthened internal connections at the low demand state (0-back) compared with the resting state (control level); whereas, from the low (0-back) to high demand state (2-back), some connections to the FPN weakened and were rewired to the DMN (whose connections all remained strong). Of note, more intensive reconfiguration of both the whole brain and core networks (but no other networks) across load levels indicated relatively poor cognitive performance. Collectively these findings indicate that the FPN and DMN have distinct roles and reconfiguration patterns across cognitively demanding loads. This study advances our understanding of the core networks and their reconfiguration patterns across cognitive loads and provides a new feature to evaluate and predict cognitive capability (e.g., WM performance) based on brain networks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.