ArticleInternational journal of stroke : official journal of the International Stroke Society2018
Post-stroke social networks, depressive symptoms, and disability in Tanzania: A prospective study.
Article in International journal of stroke : official journal of the International Stroke Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Structural and health system determinants of mental health in Tanzania: mapping policy recommendations to the WHO comprehensive mental health action plan 2013-2030.Frontiers in public health · 2026Pooled it
- Exploring the occurence and risk factors of post-stroke depression among stroke survivors in Africa: a comprehensive systematic review and meta-analysis.BMC public health · 2025Pooled it
- The impact of social relationships on the risk of stroke and post-stroke mortality: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Role of social support in poststroke depression: A meta-analysis.Frontiers in psychiatry · 2022Pooled it
- Social network intervention to improve blood pressure control after stroke: The TEAMS-BP randomized clinical trial.Social science & medicine (1982) · 2025Trial
- Efficacy of Fluoxetine for Post-Ischemic Stroke Depression in Tanzania.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022Trial
- Independent and joint associations of depressive symptoms and social isolation on trajectories of functional disability among middle-aged and older adults.Archives of public health = Archives belges de sante publique · 2026Article
- Medication Adherence Following Stroke and TIA: A Qualitative Synthesis of Patient, Caregiver and Clinician Perspectives.Neurology international · 2026Review
- Experiences of Navigating Recovery After Stroke in Tanzania: A Descriptive Qualitative Study.Nursing research and practice · 2026Article
- Early functional recovery and clinical risk profiles predict distinct trajectories of post-stroke depression: a one-year longitudinal analysis.BMC neurology · 2025Article
- Mediation Analysis of the Social Isolation Between Stigma and Return-To-Work Readiness Among Young and Middle-Aged Patients With Stroke in China.Nursing open · 2025Article
- From stroke to depression: The need for systematic screening for post-stroke depression.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2024Article
- Reversal of the detrimental effects of social isolation on ischemic cerebral injury and stroke-associated pneumonia by inhibiting small intestinalJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Barriers to Gait Training among Stroke Survivors: An Integrative Review.Journal of functional morphology and kinesiology · 2022Review
- The enigma of vascular depression in old age: a critical update.Journal of neural transmission (Vienna, Austria : 1996) · 2022Review
- Informal Support Networks of Tanzanians With Chronic Diseases: Predictors of Support Provision and Treatment Adherence.International journal of public health · 2022Article
- (Biological psychiatry global open science · 2021Article
- Microarray Profiling Reveals Distinct Circulating miRNAs in Aged Male and Female Mice Subjected to Post-stroke Social Isolation.Neuromolecular medicine · 2021Article
- Are Social Relationships an Underestimated Resource for Mental Health in Persons Experiencing Physical Disability? Observational Evidence From 22 Countries.International journal of public health · 2021Article
- MAMBO: Measuring ambulation, motor, and behavioral outcomes with post-stroke fluoxetine in Tanzania: Protocol of a phase II clinical trial.Journal of the neurological sciences · 2020Article
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Authors and funding
14 authors.
Funding
Abstract
Background Evidence suggests that social networks improve functional recovery after stroke, but this work has not been extended to low- and middle-income countries (LMICs). Post-stroke depression interferes with functional outcome but is understudied in LMICs. Aims To determine the relationships between social networks, disability, and depressive symptoms in patients surviving 90-days post-stroke in Dar es Salaam, Tanzania. Methods Participants ≥ 18 years, admitted ≤ 14 days of stroke onset, were enrolled. Disability was measured using the modified Rankin Scale, social networks by the Berkman-Syme social network index, and depressive symptoms by the Patient Health Questionnaire-9 (PHQ-9) by telephone interview at 90 days. A Kruskal-Wallis test or Spearman's correlation coefficient was used to assess the associations between social networks, depressive symptoms, and disability. Results Of 176 participants, 43% (n = 75) died, with an additional 11% (n = 20) lost to follow-up by 90 days. Among 81 survivors, 94% (n = 76, 57% male, average age 54 years) had complete information on all scales (mean and median follow-up time of 101 and 88 days). Thirty percent (n = 23, 41.9%, 95% confidence interval 20.2) had at least mild depressive symptoms (PHQ-9 ≥ 5 points). Nearly two-thirds (n = 46, 61%) reported ≥ 3 close friends. A higher social network index score was associated with fewer depressive symptoms (p < 0.0001) and showed a trend towards significance with lower disability (p = 0.061). Higher depressive symptom burden was correlated with higher disability (r = 0.52, p < 0.0001). Conclusion Post-stroke social isolation is associated with more depressive symptoms in Tanzania. Understanding social networks and the associated mechanisms of recovery in stroke is especially relevant in the context of limited resources.
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