Evidence map›Paper›PMID 29675906›Full record

ArticleAmerican journal of hematology2018

Angiotensin receptor signaling in sickle cell anemia has a reno-protective effect on urine concentrating ability but results in sickle glomerulopathy.

Swarnava Roy, Parul Rai, Marthe-Sandrine Eiymo Mwa Mpollo, Kyung-Hee Chang, Tilat Rizvi, Shiva Kumar Shanmukhappa, Katherine VandenHeuvel, Bruce Aronow, Tadashi Inagami, Jose A Cancelas and 1 more

Open access · bronzeAbstract readLetter
In one paragraph

Article in American journal of hematology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The Angiotensin ATPharmacological reviews · 2022
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Cardiac pathophysiology in sickle cell disease.Journal of thrombosis and thrombolysis · 2021
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Swarnava RoyDivision of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Research Foundation, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229.
Parul RaiDivision of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Research Foundation, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229.ORCID 0000-0002-5770-7280
Marthe-Sandrine Eiymo Mwa MpolloDivision of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Research Foundation, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229.
Kyung-Hee ChangDivision of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Research Foundation, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229.
Tilat RizviDivision of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Research Foundation, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229.
Shiva Kumar ShanmukhappaDivision of Pathology, Cincinnati Children's Research Foundation, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229.
Katherine VandenHeuvelDivision of Pathology, Cincinnati Children's Research Foundation, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229.
Bruce AronowDivision of Bioinformatics, Cincinnati Children's Research Foundation, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229.
Tadashi InagamiVanderbilt University School of Medicine, Nashville, Tennessee.
Jose A CancelasDivision of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Research Foundation, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229.
Punam MalikDivision of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Research Foundation, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229.ORCID 0000-0002-8942-2108
Cincinnati Children's Hospital Medical Center · USVanderbilt University · US

Funding

Cincinnati Center of Excellence in Hemoglobinopathies ResearchU01HL117709 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI MALIK, PUNAM · 2013 to 2017
$8.9M
Ameliorating Sickle Nephropathy and Pulmonary HypertensionR34HL108752 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI MALIK, PUNAM · 2011 to 2013
$602k
NHLBI NIH HHS R34 HL108752NHLBI NIH HHS U01 HL117709
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Kidney Concentrating AbilityAdultAnemia, Sickle CellAngiotensin II Type 1 Receptor BlockersAnimalsCaptoprilChildDisease ProgressionHumansKidney DiseasesLosartanMiceProtective AgentsReceptor, Angiotensin, Type 2Receptors, AngiotensinSignal TransductionAngiotensin II Type 1 Receptor BlockersCaptoprilLosartanProtective AgentsReceptor, Angiotensin, Type 2Receptors, Angiotensin

Identifiers

PMID29675906
PMCPMC6037553
OpenAlexW2802540856

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.