ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2018
Comparative Study of Predominant Phytochemical Compounds and Proapoptotic Potential of Broccoli Sprouts and Florets.
Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Polyphenols for the Prevention or Management of Preeclampsia: A Systematic Review and Meta-Analysis.BJOG : an international journal of obstetrics and gynaecology · 2025Pooled it
- Selenium-Sulfur Coupled Heat Treatment: A Strategy for Producing High-Quality Broccoli Sprouts.Plant foods for human nutrition (Dordrecht, Netherlands) · 2026Article
- Glucosinolate-Myrosinase Formulations for Adult Obesity: Towards Next Generation of Bioactive Therapies.Foods (Basel, Switzerland) · 2025Article
- The Effect of Plant Ontogeny on Antioxidant Capacity and Bioaccessibility of Total Phenolic Compounds and Sulforaphane in Broccoli Sprouts.Plant foods for human nutrition (Dordrecht, Netherlands) · 2025Article
- Review
- The Valorization of Wastes and Byproducts from Cruciferous Vegetables: A Review on the Potential Utilization of Cabbage, Cauliflower, and Broccoli Byproducts.Foods (Basel, Switzerland) · 2024Review
- Elucidating the role of phytocompounds fromIn silico pharmacology · 2024Article
- Potential chemopreventive effects of Broccoli extract supplementation against 7, 12 dimethyl Benz(a)anthracene (DMBA) -induced toxicity in female rats.Scientific reports · 2023Article
- Bioactive Compounds, Antioxidant Activities, and HPLC Analysis of Nine Edible Sprouts in Cambodia.Molecules (Basel, Switzerland) · 2023Article
- Effect of Hot- and Cold-Water Treatment on Broccoli Bioactive Compounds, Oxidative Stress Parameters and Biological Effects of Their Extracts.Plants (Basel, Switzerland) · 2023Article
- Chickpea and Lupin Sprouts, Stimulated by Different LED Lights, As Novel Examples of Isoflavones-Rich Functional Food, and Their Impact on Breast and Prostate Cells.Molecules (Basel, Switzerland) · 2022Article
- Investigation of the physicochemical, antioxidant, rheological, and sensory properties of ricotta cheese enriched with free and nano-encapsulated broccoli sprout extract.Food science & nutrition · 2022Article
- Broccoli Sprouts and Their Influence on Thyroid Function in Different In Vitro and In Vivo Models.Plants (Basel, Switzerland) · 2022Article
- Relative evaluation of in-vitro antioxidant potential and phenolic constituents by HPLC-DAD ofHeliyon · 2022Article
- The Impact of Kohlrabi Sprouts on Various Thyroid Parameters in Iodine Deficiency- and Sulfadimethoxine-Induced Hypothyroid Rats.Nutrients · 2022Article
- Low Temperatures Affect the Physiological Status and Phytochemical Content of Flat Leaf Kale (Foods (Basel, Switzerland) · 2022Article
- The Application of Fe-EDTA and Sodium Silicate Affects the Polyphenols Content in Broccoli and Radish Sprouts.Biomolecules · 2021Article
- Sinapic Acid Suppresses SARS CoV-2 Replication by Targeting Its Envelope Protein.Antibiotics (Basel, Switzerland) · 2021Article
- Dragon Fruits as a Reservoir of Natural Polyphenolics with Chemopreventive Properties.Molecules (Basel, Switzerland) · 2021Article
- Health Promoting vs Anti-nutritive Aspects of Kohlrabi Sprouts, a Promising Candidate for Novel Functional Food.Plant foods for human nutrition (Dordrecht, Netherlands) · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study compares lyophilized broccoli sprouts and florets in terms of their chemical composition, cytotoxic and proapoptotic potential against hepatocellular carcinoma HepG2, colorectal cancer SW480, and skin fibroblast BJ cells. Sinapic and isochlorogenic acids were predominant phenolics in the sprouts and florets, respectively. The amount of sulforaphane in the sprouts was significantly higher vs. florets. Oleic and linoleic acids dominated in the sprouts, while caproic, stearic and oleic acids in the florets. Broccoli sprouts were selectively cytotoxic on HepG2 and SW480 cells, with proapoptotic effect for the latter, while the florets were less selective, but more active, with profound proapoptotic effect for HepG2 cells (77.4%). Thus, lyophilized broccoli sprouts may be effectively used in dietary chemoprevention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.