Evidence map›Paper›PMID 29675622›Full record

ArticleClinical rheumatology2018

Rheumatoid arthritis in the indigenous qom population of Rosario, Argentina: aggressive and disabling disease with inadequate adherence to treatment in a community-based cohort study.

Rosana Quintana, Mario Goñi, Nora Mathern, Marisa Jorfen, Silvana Conti, Romina Nieto, Alvaro Sanabria, Cristina Prigione, Adriana M R Silvestre, Vanina García and 6 more

Abstract read
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In one paragraph

Article in Clinical rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Insights into low back pain management in Argentina.Brazilian journal of physical therapy
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 4 countries.

Rosana QuintanaHospital Provincial de Rosario, Leandro N Alen 1450, Rosario, Santa Fe, Argentina. rosanaquintana@gmail.com.
Mario GoñiCentro de Especialidades Médicas Ambulatorias de Rosario, Secretaría de Salud Pública, Municipalidad de Rosario, Santa Fe, Argentina.
Nora MathernOrtopedia y Fisiatría, Instituto de Reumatología, Rosario, Santa Fe, Argentina.
Marisa JorfenCentro de Especialidades Médicas Ambulatorias de Rosario, Secretaría de Salud Pública, Municipalidad de Rosario, Santa Fe, Argentina.
Silvana ContiHospital Provincial de Rosario, Leandro N Alen 1450, Rosario, Santa Fe, Argentina.
Romina NietoHospital Provincial de Rosario, Leandro N Alen 1450, Rosario, Santa Fe, Argentina.
Alvaro SanabriaHospital Provincial de Rosario, Leandro N Alen 1450, Rosario, Santa Fe, Argentina.
Cristina PrigioneHospital Provincial de Rosario, Leandro N Alen 1450, Rosario, Santa Fe, Argentina.
Adriana M R SilvestreMinisterio de Salud, Gobierno de la Provincia de Santa Fe, Santa Fe, Argentina.
Vanina GarcíaMinisterio de Salud, Gobierno de la Provincia de Santa Fe, Santa Fe, Argentina.
Guillermo Pons-EstelHospital Provincial de Rosario, Leandro N Alen 1450, Rosario, Santa Fe, Argentina.
Ricard CerveraServicio Enfermedades Autoinmunes, Hospital Clínic, University of Barcelona, Barcelona, Catalonia, Spain.
Conrado GarcíaHospital General de México "Dr. Eduardo Liceaga", Mexico City, Mexico.
Ingris Peláez-BallestasHospital General de México "Dr. Eduardo Liceaga", Mexico City, Mexico.
Graciela S AlarcónDepartment of Medicine, Division of Clinical Immunology and Rheumatology, School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Bernardo A Pons-EstelHospital Provincial de Rosario, Leandro N Alen 1450, Rosario, Santa Fe, Argentina.
Hospital Provincial de Rosario · ARHospital General de México · MXMinisterio de Salud · ARUniversitat de Barcelona · ESInstituto de Oncología de Rosario · ARUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To describe the baseline and follow up epidemiological/clinical characteristics of rheumatoid arthritis (RA) in a community-based cohort of the qom population. RA (ACR criteria) patients identified (n = 40) or not (n = 25) in the previous study were included. Baseline and follow-up visits (3, 6, and 12 months) were performed. Treatment adherence and modification, disability (Health Assessment Questionnaire Disability Index-HAQ-DI), and Disease Activity [DAS-28 (ESR)] were ascertained. At 12 months, complete and incomplete lost to follow-up patients were identified. The estimated RA prevalence was 3%. The patients' mean (SD) disease duration was 110.5 (17.9) and their median delay in diagnosis 30.4 (IQR 52.8) months; mean (SD) age and years of formal education were 39.8 (1.6) and 5.3 (SD 0.3); 58 (89.2%) were female, and 89.2% were seropositive. At baseline, their mean DAS-28 (ESR) was 4.8 (SD 0.9) with 67.7% having high disease activity and 32.3% moderate; 76.9% reported HAQ-DI ≥ 0.8. At 12 months, three patients have died; 13 (20.9%) were "completely" and 19 (30.6%) "incompletely" lost to follow-up. There were favorable changes over time for disease activity (p ˂ 0.001), HAQ-DI (p ˂ 0.001), and treatment modifications (p ˂ 0.001) but no changes in treatment adherence (p = 0.260). The main cause of lost to follow-up was migration. This population has one of the highest RA prevalence rate reported. Patients had an aggressive and disabling disease, with poor adherence to treatment. Improvements of clinical parameters over time were observed.

Indexed as

AdolescentAdultArgentinaArthritis, RheumatoidCohort StudiesFemaleHumansMaleMiddle AgedPatient CompliancePilot ProjectsYoung AdultCommunity-based cohortIndigenous communityLatin AmericaqomRheumatoid arthritisTreatment adherence

Identifiers

PMID29675622
OpenAlexW2801619461

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.