Observational studyInternational journal of colorectal disease2018
Late assessment of quality of life in patients with rectal carcinoma: comparison between sphincter preservation and definitive colostomy.
Observational study in International journal of colorectal disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Quality of life in restorative versus non-restorative resections for rectal cancer: systematic review.BJS open · 2021Pooled it
- Bibliometric and visual analysis of palliative care in colorectal cancer research from 2015 to April 2025.Hereditas · 2025Article
- The Quality of Life of Patients with Surgically Treated Colorectal Cancer: A Narrative Review.Journal of clinical medicine · 2022Review
- Quality of Life after Rectal Cancer Resection Comparing Anterior Resection, Abdominoperineal Resection, and Complicated Cases.Visceral medicine · 2022Article
- Health-related quality of life in advanced colorectal cancer patients in China: a nationwide hospital-based survey.Annals of translational medicine · 2022Article
- Management guidelines for low anterior resection syndrome - the MANUEL project.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2021Article
- The effect of online training-based continuous nursing care for rectal cancer-patients undergoing permanent colostomy.American journal of translational research · 2021Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePatients with cancer of the lower and middle rectum who are candidates for curative surgery often have negative opinions on definitive colostomy. The purpose of this study is to compare the quality of life (QoL) of patients who undergo standard treatment for rectal cancer with sphincter preservation or definitive colostomy.
methodsA total of 125 patients with adenocarcinoma of the lower or middle rectum who underwent radical surgery with curative intent with a follow-up ≥ 1 year were recruited: 83 patients (group 1) were subjected to low anterior resection and low colorectal or coloanal anastomosis-thus preserving their sphincter-and 42 (group 2) were treated with abdominoperineal resection, followed by terminal definitive colostomy. QoL was assessed with the EORTC QLQ-C30 and QLQ-CR29 questionnaires.
resultsHealth and global quality of life were similar between groups; however, patients who underwent definitive colostomy had higher scores on the emotional (p value = 0.016) and cognitive function scales (p value = 0.017). Patients with sphincter preservation presented with more symptoms that were related to stool frequency (p value < 0.001), intestinal constipation (p value = 0.005), fecal incontinence (p value = 0.001), buttock pain (p value = 0.023), and nausea and vomiting (p value = 0.036), whereas patients with permanent colostomy had higher scores for dysuria (p value = 0.033).
conclusionAlthough global QoL scores did not differ between groups, patients who underwent definitive colostomy had significantly better functional and symptom scale scores, reflecting greater function with fewer symptoms.
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