ArticleIntensive care medicine2018
The Surviving Sepsis Campaign Bundle: 2018 update.
9 registry-linked trialsAbstract readEditorial
In one paragraph
Article in Intensive care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 9 registered trials, which are not on this map. Cited by 504 papers, 10 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
504citing papers in PubMed, 10 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Hemodynamic Resuscitation and Monitoring in Early Sepsis
Resuscitation Failure, Protein Carbonyl and Receptor Interacting Protein Kinase 3 as Mortality Predictor in Septic Patient
Evaluation of Presepsin and Syndecan-1 as Biomarkers for Early Diagnosis and Prognosis of Sepsis Following Major Surgeries
Fast-track Absolute Neutrophil Count in Suspected Neutropenic Fever (The FRANCiS-NF Trial): A Single-centre, Pragmatic, Open-label, Randomised, Controlled Trial
Ultrasonographic Predictors of Intravenous Fluid Responsiveness in Septic Shock and Its Correlation to Central Venous Pressure
The Clinical and Pharmacoeconomic Impact of Rapid Diagnostic Test (Multiplex PCR FilmArray) on Antimicrobial Decision Making Compared to Conventional Decision Making Among Critically Ill Patients
Guideline-recommended Basic Parameter Adherence in Neurocritical Care Patients: German-wide Observational Multicenter Individual Participant Data Meta-analysis
Functional Hemodynamic Assessment in Shocked Patients in the Pediatric Intensive Care Unit
Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock: A Multicenter Prospective Randomized Trial (CARBON)
Who cites it
504 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Construction of a sensitive indicator evaluation system for sepsis care quality: a three-stage mixed-method Delphi study.Frontiers in medicine · 2026Pooled it
- Pooled it
- [S3 guideline on sepsis-prevention, diagnosis, therapy, and follow-up care-update 2025].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025Guideline
- Effect of restrictive fluid resuscitation on severe acute kidney injury in septic shock: a systematic review and meta-analysis.BMJ open · 2025Pooled it
- Application of norepinephrine in the treatment of septic shock: a meta-analysis.Irish journal of medical science · 2025Pooled it
- Therapeutic Role of HAT Therapy in Sepsis: A Systematic Review and Meta-Analysis.Current medicinal chemistry · 2025Pooled it
- Early management of adult sepsis and septic shock: Korean clinical practice guidelines.Acute and critical care · 2024Guideline
- [Early source control of infection in patients seen in the emergency department: a systematic review].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024Pooled it
- Sepsis Alert Systems, Mortality, and Adherence in Emergency Departments: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Study based on bibliometric analysis: potential research trends in fluid management for sepsis.Frontiers in medicine · 2024Pooled it
- Midodrine for Sepsis Treatment and Early Vasopressor Weaning (MID-STEP): protocol for a pragmatic randomised clinical trial.BMJ open · 2026Trial
- Real-time machine learning-assisted sepsis alert enhances the timeliness of antibiotic administration and diagnostic accuracy in emergency department patients with sepsis: a cluster-randomized trial.Internal and emergency medicine · 2024Trial
- Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: a stepped wedge cluster randomized clinical trial.Intensive care medicine · 2024Trial
- Effects of dynamic versus static parameter-guided fluid resuscitation in patients with sepsis: A randomized controlled trial.F1000Research · 2024Trial
- Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL).Intensive care medicine · 2024Trial
- Optimizing Fluid Management Guided by Volumetric Parameters in Patients with Sepsis and ARDS.International journal of molecular sciences · 2023Trial
- Comparison of Short-Course and Conventional Antimicrobial Duration in Mild and Moderate Complicated Intra-Abdominal Infections: A randomised controlled trial.Sultan Qaboos University medical journal · 2023Trial
- Evaluating the effects of Esmolol on cardiac function in patients with Septic cardiomyopathy by Speck-tracking echocardiography-a randomized controlled trial.BMC anesthesiology · 2023Trial
- Advancements in early biomarkers of acute kidney injury: from traditional indicators to a paradigm shift in lactate metabolism.Annals of medicine · 2026Review
- Prevalence of MRSA Bacteremia and Predictors of In-Hospital Mortality Among Critically Ill Adults in a Tanzanian Intensive Care Unit: A Retrospective Cross-Sectional Study.Health science reports · 2026Article
444 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
3 authors.
Mitchell M LevyDepartment of Medicine, Division of Pulmonary/Critical Care Medicine, Alpert Medical School at Brown University, Providence, RI, USA. mitchell_levy@brown.edu.
Laura E EvansNew York University School of Medicine, New York, NY, USA.
Andrew RhodesSt. George's University Hospitals NHS Foundation Trust and St George's University of London, London, UK.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
SepsisGuideline AdherenceHumansPractice Guidelines as TopicShock, Septic
Identifiers
PMID
29675566What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT04143035ClinicalTrials.gov
NCT04169412ClinicalTrials.gov
NCT04718623ClinicalTrials.gov
NCT05393505ClinicalTrials.gov
NCT05612529ClinicalTrials.gov
NCT05759494ClinicalTrials.gov
and 3 more above
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.