Evidence map›Paper›PMID 29675563›Full record

ArticleInternational ophthalmology2019

Trans-epithelial corneal collagen cross-linking with iontophoresis for progressive keratoconus.

Mohammed Ali Abu Ameerh, Muawyah Dawoud Al Bdour, Maha Al-Till, Muhannad Al Faouri

Abstract read
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In one paragraph

Article in International ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mohammed Ali Abu AmeerhOphthalmology Department, The University of Jordan, P.O Box 13046, Amman, 11942, Jordan. mohammd_73@yahoo.com.
Muawyah Dawoud Al BdourOphthalmology Department, The University of Jordan, P.O Box 13046, Amman, 11942, Jordan.
Maha Al-TillAl Taif Eye Center, Amman, Jordan.
Muhannad Al FaouriAl Taif Eye Center, Amman, Jordan.
University of Jordan · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the efficacy of trans-epithelial corneal collagen cross-linking (CXL) with Iontophoresis among patients with progressive keratoconus.

methodsIt is a prospective interventional study, which is based on 41 eyes of 23 patients, suffering from progressive keratoconus and treated with trans-epithelial corneal cross-linking, using iontophoresis with ETDA and trometamol-enriched riboflavin 5 phosphates 0.1% hypotonic solution (Ricrolin+, Soot Italia SpA, Italy).

resultsThe mean of uncorrected distance visual acuity and best corrected distant visual acuity was improved at 6 months with statistically significant differences from baseline (p < 0.05). There was no statistically significant difference in keratometric values, including K

conclusionThe data indicated that corneal collagens cross-linking with iontophoresis using Ricroli+ may be an effective method in halting the progression of keratoconus without the side effects of epithelial removal, which may be encountered in the standard epi-off CXL procedure.

Indexed as

Visual AcuityAdultCollagenCorneal TopographyCross-Linking ReagentsEpithelium, CornealFemaleFollow-Up StudiesHumansIontophoresisKeratoconusMalePhotosensitizing AgentsProspective StudiesRiboflavinTime FactorsCollagenCross-Linking ReagentsPhotosensitizing AgentsRiboflavinCorneal cross-linkingCorneal thicknessIontophoresisKeratoconusTrans-epithelial cross-linking

Identifiers

PMID29675563
OpenAlexW2799976235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.