Evidence map›Paper›PMID 29675547›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018

The association between fatigue and pain symptoms and decreased physical activity after cancer.

Sally A D Romero, Lee Jones, Joshua M Bauml, Q Susan Li, Roger B Cohen, Jun J Mao

Open access · greenAbstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.

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  5. Joint nausea and fatigue profiles during chemotherapy identify patients with a higher symptom burden.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sally A D RomeroDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Lee JonesDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Joshua M BaumlDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Q Susan LiDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Roger B CohenDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jun J MaoDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. maoj@mskcc.org.
Memorial Sloan Kettering Cancer Center · USUniversity of Pennsylvania · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
UNIVERSITY OF PENNSYLVANIA CAN CTR SUPPORT GRANTP30CA016520 · NCI · UNIVERSITY OF PENNSYLVANIA · PI SHELLEY L BERGER · 1985 to 2026
$222.3M
Psychosocial Palliative & Community Research in CancerT32CA009461 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI JENNIFER L HAY, Jamie S. Ostroff · 1985 to 2026
$10.1M
Estrogen Deprivation and Aromatase Inhibitor associated ArthralgiaR01CA158243 · NCI · UNIVERSITY OF PENNSYLVANIA · PI MAO, JUN J · 2011 to 2015
$2.2M
National Cancer Institute 2P30CA016520-40National Cancer Institute 3P30CA008748-50National Institutes of Health 5T32CA9461-32NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA016520NCI NIH HHS R01 CA158243NCI NIH HHS T32 CA009461
6 · The paper itself

Abstract

purposePatients with cancer frequently experience symptoms such as fatigue and pain that can influence their ability to maintain their usual physical activity (PA). This study aimed to evaluate whether symptoms of fatigue and pain are associated with decreased PA among patients with cancer.

methodsWe recruited patients with a cancer diagnosis from one academic medical center and 11 affiliated community hospitals to participate in a cross-sectional survey. Multivariate logistic regression models were used to examine the association between symptoms, demographics, and clinical characteristics and decreased PA since cancer diagnosis.

resultsAmong 629 participants, 499 (79%) reported a decreased level of PA since their cancer diagnosis. In the past 7 days from the time of the survey, 78% of participants reported moderate to very severe fatigue, and 68% reported a pain level 4 or greater on a scale of 0 to 10. Adjusted for covariates, patients with fatigue (Adjusted Odds Ratio, AOR 4.01, 95% CI 2.41-6.65) and pain (AOR 1.89, 95% CI 1.14-3.12) had higher odds of reporting decreased PA since diagnosis. Receipt of chemotherapy or currently receiving active cancer treatment was also associated with decreased PA (p < 0.05).

conclusionsFatigue and pain are associated with decreased PA among patients with cancer, even after adjusting for cancer treatment. Interventions focused on managing these symptoms may help promote maintenance of PA throughout cancer treatment and beyond.

Indexed as

AdultAgedAged, 80 and overCross-Sectional StudiesExerciseFatigueFemaleHumansMaleMiddle AgedNeoplasmsPainSurveys and QuestionnairesYoung AdultCancerFatiguePainPhysical activitySupportive care

Identifiers

PMID29675547
PMCPMC6117206
OpenAlexW2799676658

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.