Evidence map›Paper›PMID 29675438›Full record

ArticleJournal of immunology research2018

FGFRL1 Promotes Ovarian Cancer Progression by Crosstalk with Hedgehog Signaling.

Haiyan Tai, Zhiyong Wu, Su'an Sun, Zhigang Zhang, Congjian Xu

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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  5. Review
  6. Aberrant Expression of FGFRL1 in Esophageal Cancer and Its Regulation by miR-107.Asian Pacific journal of cancer prevention : APJCP · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Haiyan TaiObstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.ORCID 0000-0003-0737-2555
Zhiyong WuObstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Su'an SunDepartment of Pathology, The First Hospital of Huai'an City, Nanjing Medical University, Huai'an, 223001 Jiangsu, China.
Zhigang ZhangState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID 0000-0001-8965-223X
Congjian XuObstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.ORCID 0000-0002-7954-5892
Obstetrics and Gynecology Hospital of Fudan University · CNNanjing Medical University · CNShanghai Jiao Tong University · CNShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibroblast growth factor receptor-like-1 (FGFRL1) has been identified as the fifth fibroblast growth factor receptor. So far, little is known about its biological functions, particularly in cancer development. Here, for the first time, we demonstrated the roles of FGFRL1 in ovarian carcinoma (OC). An array and existing databases were used to investigate the expression profile of FGFRL1 and the relationship between FGFRL1 expression and clinicopathological parameters. FGFRL1 was significantly upregulated in OC patients, and high FGFRL1 expression was correlated with poor prognosis.

Indexed as

CarcinogenesisAnimalsApoptosisCell Line, TumorCell MovementCell ProliferationCohort StudiesDisease ProgressionFemaleGene Expression Regulation, NeoplasticHedgehogsHeterograftsHumansMiceMicroarray AnalysisNeoplasm TransplantationFGFRL1 protein, humanReceptor, Fibroblast Growth Factor, Type 5RNA, Small Interfering

Identifiers

PMID29675438
PMCPMC5838460
OpenAlexW2792443369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.