Evidence map›Paper›PMID 29675436›Full record

ReviewJournal of immunology research2018

Prevention and Treatment of Osteoporosis Using Chinese Medicinal Plants: Special Emphasis on Mechanisms of Immune Modulation.

Hongyan Zhao, Ning Zhao, Peng Zheng, Xiaohong Xu, Meijie Liu, Dan Luo, Huihui Xu, Dahong Ju

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Review
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  6. Article
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  9. Article
  10. Review
  11. Metabolic bone disorders and the promise of marine osteoactive compounds.Cellular and molecular life sciences : CMLS · 2023
    Review
  12. Article
  13. Nutrients · 2023
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Network Pharmacological Study ofBioMed research international · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Hongyan ZhaoExperimental Research Center, China Academy of Chinese Medical Sciences, Beijing 100700, China.ORCID 0000-0002-7459-0336
Ning ZhaoInstitute of Clinical Basic Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Peng ZhengJilin Provincial Hospital of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130021, China.
Xiaohong XuChangchun University of Chinese Medicine, Changchun 130117, China.
Meijie LiuExperimental Research Center, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Dan LuoTraditional Chinese Medicine Hospital of Changping District, Beijing 102200, China.
Huihui XuExperimental Research Center, China Academy of Chinese Medical Sciences, Beijing 100700, China.ORCID 0000-0002-4963-3437
Dahong JuExperimental Research Center, China Academy of Chinese Medical Sciences, Beijing 100700, China.ORCID 0000-0001-5903-8175
Chinese Academy of Medical Sciences & Peking Union Medical College · CNBeijing Chang'an Integrated Traditional Chinese and Western Medicine Hospital · CNChangchun University of Chinese Medicine · CNThe Affiliated Hospital to Changchun University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have examined the pathogenesis of osteoporosis. The causes of osteoporosis include endocrine factors, nutritional status, genetic factors, physical factors, and immune factors. Recent osteoimmunology studies demonstrated that the immune system and immune factors play important regulatory roles in the occurrence of osteoporosis, and people should pay more attention to the relationship between immunity and osteoporosis. Immune and bone cells are located in the bone marrow and share numerous regulatory molecules, signaling molecules, and transcription factors. Abnormal activation of the immune system alters the balance between osteoblasts and osteoclasts, which results in an imbalance of bone remodeling and osteoporosis. The incidence of osteoporosis is also increasing with the aging of China's population, and traditional Chinese medicine has played a vital role in the prevention and treatment of osteoporosis for centuries. Chinese medicinal plants possess unique advantages in the regulation of the immune system and the relationships between osteoporosis and the immune system. In this review, we provide a general overview of Chinese medicinal plants in the prevention and treatment of osteoporosis, focusing on immunological aspects.

Indexed as

Medicine, Chinese TraditionalAnimalsBone RemodelingDrugs, Chinese HerbalHumansImmune SystemImmunomodulationOsteoblastsOsteoclastsOsteoporosisDrugs, Chinese Herbal

Identifiers

PMID29675436
PMCPMC5838472
OpenAlexW2791985442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.