ReviewFrontiers in pediatrics2018
Neonatal Hemodynamics: From Developmental Physiology to Comprehensive Monitoring.
Review in Frontiers in pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06200519 (A Longitudinal Observational Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography in Neonates Born at 35 Weeks Gestation or Above), which is not on this map. Cited by 63 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Longitudinal Observational Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography in Neonates Born at 35 Weeks Gestation or Above
Who cites it
63 citing papers in PubMed, 4 syntheses or guidelines pooled it, 114 citations in OpenAlex.
- Role of functional echocardiography in neonatal shock: a systematic review and meta-analysis.Pediatric research · 2026Pooled it
- A recommendation for the use of electrical biosensing technology in neonatology.Pediatric research · 2025Guideline
- Cerebral fractional tissue oxygen extraction (cFTOE) during immediate fetal-to-neonatal transition: a systematic qualitative review of the literature.European journal of pediatrics · 2024Pooled it
- Accuracy and Trending Ability of Electrical Biosensing Technology for Non-invasive Cardiac Output Monitoring in Neonates: A Systematic Qualitative Review.Frontiers in pediatrics · 2022Pooled it
- Care of the Newborn and Cord During the Third Stage of Labour (Scientific Impact Paper No. 78).BJOG : an international journal of obstetrics and gynaecology · 2026Review
- Understanding physiological adaptations of pregnancy to the chronic hypoxia of high altitude to inform obstetrical and neonatal care.Physiological reviews · 2026Review
- Cardiorespiratory coupling during high-frequency oscillatory ventilation with volume guarantee in extremely preterm infants.European journal of pediatrics · 2026Article
- A Comprehensive Review of the Approach to Ultrasonography in Neonatal Shock: The Partnership Between Targeted Neonatal Echocardiography and Point-of-Care Ultrasound.Children (Basel, Switzerland) · 2026Review
- Fetomaternal hemorrhage: pathogenesis, diagnosis, and clinical management.Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- Risk factors for 30-day mortality following major neonatal surgery: insights from a 10-year cohort in southern Tunisia.Surgery today · 2026Article
- Delayed Cord Clamping and Early Neonatal Outcomes in Infants Born Before 30 Weeks of Gestation: A Retrospective Cohort Study.Children (Basel, Switzerland) · 2026Article
- Randomised trial of early rapid saline bolus versus epinephrine during resuscitation in perinatal haemorrhagic cardiac arrest in newborn lambs.Archives of disease in childhood. Fetal and neonatal edition · 2026Article
- Targeted Neonatal Echocardiography and Neonatal Hemodynamics in the Kingdom of Saudi Arabia:Saudi medical journal · 2026Article
- Shape of the hemodynamic response function in deaf infants eligible for cochlear implantation.Neurophotonics · 2026Article
- Non-invasive multimodal hemodynamic monitoring for vulnerable preterm infants in the transitional period.Pediatric research · 2025Article
- Transitional haemodynamic profiles of intrauterine growth-restricted preterm infants: correlation with antenatal Doppler characteristics.Pediatric research · 2025Article
- A Novel Prenatal Pipeline for Three-Dimensional Hemodynamic Modeling of the Fetal Aorta.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025Article
- Article
- Systemic hypotension and patterns of cerebral blood perfusion in newborns.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Cardiorespiratory Stability in Critically Ill Preterm Infants following Dexmedetomidine Initiation.American journal of perinatology · 2025Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maintenance of neonatal circulatory homeostasis is a real challenge, due to the complex physiology during postnatal transition and the inherent immaturity of the cardiovascular system and other relevant organs. It is known that abnormal cardiovascular function during the neonatal period is associated with increased risk of severe morbidity and mortality. Understanding the functional and structural characteristics of the neonatal circulation is, therefore, essential, as therapeutic hemodynamic interventions should be based on the assumed underlying (patho)physiology. The clinical assessment of systemic blood flow (SBF) by indirect parameters, such as blood pressure, capillary refill time, heart rate, urine output, and central-peripheral temperature difference is inaccurate. As blood pressure is no surrogate for SBF, information on cardiac output and systemic vascular resistance should be obtained in combination with an evaluation of end organ perfusion. Accurate and reliable hemodynamic monitoring systems are required to detect inadequate tissue perfusion and oxygenation at an early stage before this result in irreversible damage. Also, the hemodynamic response to the initiated treatment should be re-evaluated regularly as changes in cardiovascular function can occur quickly. New insights in the understanding of neonatal cardiovascular physiology are reviewed and several methods for current and future neonatal hemodynamic monitoring are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.