Evidence map›Paper›PMID 29675354›Full record

ArticleQuantitative imaging in medicine and surgery2018

Quantification of liver iron concentration using the apparent susceptibility of hepatic vessels.

Saifeng Liu, Chaoyue Wang, Xiaoqi Zhang, Panli Zuo, Jiani Hu, E Mark Haacke, Hongyan Ni

Open access · hybridAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Toward a realistic in silico abdominal phantom for QSM.Magnetic resonance in medicine · 2023
    Article
  8. Article
  9. Susceptibility-weighted Imaging for Renal Iron Overload Assessment: A Pilot Study.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022
    Article
  10. Article
  11. Article
  12. Topics on quantitative liver magnetic resonance imaging.Quantitative imaging in medicine and surgery · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Saifeng LiuThe MRI Institute for Biomedical Research, Bingham Farms, MI, USA.
Chaoyue WangSchool of Biomedical Engineering, McMaster University, Hamilton, ON, Canada.
Xiaoqi ZhangDepartment of Radiology, Tianjin First Central Hospital, Tianjin 300192, China.
Panli ZuoSiemens Healthcare, MR Collaborations NE Asia, Beijing 100010, China.
Jiani HuDepartment of Radiology, Wayne State University, Detroit, MI, USA.
E Mark HaackeThe MRI Institute for Biomedical Research, Bingham Farms, MI, USA.
Hongyan NiDepartment of Radiology, Tianjin First Central Hospital, Tianjin 300192, China.
Magnetic Resonance Imaging Institute for Biomedical Research · USMcMaster University · CASiemens Healthcare (United States) · USTianjin First Center Hospital · CNTianjin Medical University · CNWayne State University · US

Funding

(PQC5 in RFA-CA-12-020) Using MR phase to detect ferritin tagged breast cancer ceR21CA184682 · NCI · WAYNE STATE UNIVERSITY · PI HU, JIANI, WANG, JIANJUN · 2014 to 2015
$364k
NCI NIH HHS R21 CA184682
6 · The paper itself

Abstract

backgroundThe quantification of liver iron concentration (LIC) is important for the monitoring of the body iron level in patients with iron overload. Conventionally, LIC is quantified through R2 or R2* mapping using MRI. In this paper, we demonstrate an alternative approach for LIC quantification through measuring the apparent susceptibility of hepatic vessels using quantitative susceptibility mapping (QSM).

methodsQSM was performed in the liver region with the iterative susceptibility weighted imaging and mapping (iSWIM) algorithm, using the geometry of the vessels extracted from magnitude images as constraints. The susceptibilities of liver tissue were estimated from the apparent susceptibility of the hepatic veins and then converted to LIC. The accuracy of the proposed method was first validated using simulations, and then confirmed using

resultsSimulation results showed that the use of a 3D data acquisition protocol with higher image resolution led to improved accuracy in LIC quantification using QSM. Both simulations and

conclusionsThe proposed method offers a reliable and flexible way to quantify LIC and has the potential to extend the range of LIC that can be accurately measured using R2* and QSM.

Indexed as

Liver iron concentration (LIC)quantitative susceptibility mapping (QSM)R2* mapping

Identifiers

PMID29675354
PMCPMC5891678
OpenAlexW2794241930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.