Evidence map›Paper›PMID 29675317›Full record

ArticleBiomedical optics express2018

High-pulse energy supercontinuum laser for high-resolution spectroscopic photoacoustic imaging of lipids in the 1650-1850 nm region.

Manoj Kumar Dasa, Christos Markos, Michael Maria, Christian R Petersen, Peter M Moselund, Ole Bang

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07784179 (Ultrasound and Photoacoustic Imaging of Hydrocephalus), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07784179 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Ultrasound and Photoacoustic Imaging of Hydrocephalus

TypeinterventionalSponsorMichael McDowellRan2026 to 2029Enrolled250ConditionsHydrocephalus in Infants, Hydrocephalus in ChildrenArmsPAUS imaging
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Fiber laser technologies for photoacoustic microscopy.Visual computing for industry, biomedicine, and art · 2021
    Review
  11. Dual-comb photoacoustic spectroscopy.Nature communications · 2020
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Manoj Kumar DasaDepartment of Photonics Engineering, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Christos MarkosDepartment of Photonics Engineering, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Michael MariaDepartment of Photonics Engineering, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Christian R PetersenDepartment of Photonics Engineering, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Peter M MoselundNKT Photonics A/S, Blokken 84, Birkerød 3460, Denmark.
Ole BangDepartment of Photonics Engineering, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Technical University of Denmark · DKNKT Holding (Denmark) · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We propose a cost-effective high-pulse energy supercontinuum (SC) source based on a telecom range diode laser-based amplifier and a few meters of standard single-mode optical fiber, with a pulse energy density as high as ~25 nJ/nm in the 1650-1850 nm regime (factor >3 times higher than any SC source ever used in this wavelength range). We demonstrate how such an SC source combined with a tunable filter allows high-resolution spectroscopic photoacoustic imaging and the spectroscopy of lipids in the first overtone transition band of C-H bonds (1650-1850 nm). We show the successful discrimination of two different lipids (cholesterol and lipid in adipose tissue) and the photoacoustic cross-sectional scan of lipid-rich adipose tissue at three different locations. The proposed high-pulse energy SC laser paves a new direction towards compact, broadband and cost-effective source for spectroscopic photoacoustic imaging.

Indexed as

(140.3510) Lasers, fiber(170.5120) Photoacoustic imaging(190.4370) Nonlinear optics, fibers(320.6629) Supercontinuum generation

Identifiers

PMID29675317
PMCPMC5905921
OpenAlexW2790265183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.