Evidence map›Paper›PMID 29675307›Full record

ArticleBiomedical optics express2018

Image restoration approach to address reduced modulation contrast in structured illumination microscopy.

Nurmohammed Patwary, Ana Doblas, Chrysanthe Preza

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nurmohammed PatwaryDepartment of Electrical and Computer Engineering, The University of Memphis, Memphis, TN 38152, USA.
Ana DoblasDepartment of Electrical and Computer Engineering, The University of Memphis, Memphis, TN 38152, USA.
Chrysanthe PrezaDepartment of Electrical and Computer Engineering, The University of Memphis, Memphis, TN 38152, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The performance of structured illumination microscopy (SIM) is hampered in many biological applications due to the inability to modulate the light when imaging deep into the sample. This is in part because sample-induced aberration reduces the modulation contrast of the structured pattern. In this paper, we present an image restoration approach suitable for processing raw incoherent-grid-projection SIM data with a low fringe contrast. Restoration results from simulated and experimental ApoTome SIM data show results with improved signal-to-noise ratio (SNR) and optical sectioning compared to the results obtained from existing methods, such as 2D demodulation and 3D SIM deconvolution. Our proposed method provides satisfactory results (quantified by the achieved SNR and normalized mean square error) even when the modulation contrast of the illumination pattern is as low as 7%.

Indexed as

(080.1010) Aberrations(100.1830) Deconvolution(100.3010) Image reconstruction techniques(110.1758) Computational imaging(180.2520) Fluorescence microscopy(180.6900) Three-dimensional microscopy

Identifiers

PMID29675307
PMCPMC5905911

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.