Evidence map›Paper›PMID 29675306›Full record

ArticleBiomedical optics express2018

Super-resolution fluorescence microscopy by stepwise optical saturation.

Yide Zhang, Prakash D Nallathamby, Genevieve D Vigil, Aamir A Khan, Devon E Mason, Joel D Boerckel, Ryan K Roeder, Scott S Howard

Abstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Biocompatible, Multi-Mode, Fluorescent,Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  6. Reporting on the future of integrative structural biology ORAU workshop.Frontiers in bioscience (Landmark edition) · 2020
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yide ZhangDepartment of Electrical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA.
Prakash D NallathambyDepartment of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA.
Genevieve D VigilDepartment of Electrical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA.
Aamir A KhanDepartment of Electrical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA.
Devon E MasonDepartment of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA.
Joel D BoerckelDepartments of Orthopaedic Surgery and Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.
Ryan K RoederDepartment of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA.
Scott S HowardDepartment of Electrical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA.

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
NCATS NIH HHS UL1 TR001108
6 · The paper itself

Abstract

Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the super-resolution microscopy is not feasible in many applications. In this paper, we propose and demonstrate a saturation-based super-resolution fluorescence microscopy technique that can be easily implemented and requires neither additional hardware nor complex post-processing. The method is based on the principle of stepwise optical saturation (SOS), where

Indexed as

(100.6640) Superresolution(170.2520) Fluorescence microscopy(180.4315) Nonlinear microscopy(190.4180) Multiphoton processes

Identifiers

PMID29675306
PMCPMC5905910

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.