Evidence map›Paper›PMID 29675304›Full record

ArticleBiomedical optics express2018

Identifying intestinal fibrosis and inflammation by spectroscopic photoacoustic imaging: an animal study

Yunhao Zhu, Laura A Johnson, Ziyi Huang, Jonathan M Rubin, Jie Yuan, Hao Lei, Jun Ni, Xueding Wang, Peter D R Higgins, Guan Xu

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Optical and Photoacoustic Imaging.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  2. Article
  3. Guided Multispectral Optoacoustic Tomography for 3D Imaging of the Murine Colon.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Surgical spectral imaging.Medical image analysis · 2020
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Noninvasive staging of pressure ulcers using photoacoustic imaging.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2019
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Yunhao ZhuDepartment of Electronic Science and Engineering, Nanjing University, Nanjing, Jiangsu 21000, China.
Laura A JohnsonDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Ziyi HuangDepartment of Electrical and Computer Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Jonathan M RubinDepartment of Radiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Jie YuanDepartment of Electronic Science and Engineering, Nanjing University, Nanjing, Jiangsu 21000, China.
Hao LeiDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Jun NiDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Xueding WangDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Peter D R HigginsDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Guan XuDepartment of Radiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
University of Michigan–Ann Arbor · USNanjing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crohn's disease (CD) is a chronic autoimmune disease characterized by obstructing intestinal strictures. Conventional imaging modalities can identify the strictures but cannot characterize whether a stricture is predominantly inflammatory or fibrotic. The purpose of this study is to examine the capability of photoacoustic (PA) imaging to characterize intestinal fibrosis and inflammation

Indexed as

(170.3880) Medical and biological imaging(170.5120) Photoacoustic imaging(170.6510) Spectroscopy, tissue diagnostics(170.7170) Ultrasound

Identifiers

PMID29675304
PMCPMC5905908
OpenAlexW2792154534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.