ArticleJournal of ophthalmology2018
Effect of Altered Retinal Cones/Opsins on Refractive Development under Monochromatic Lights in Guinea Pigs.
Article in Journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 45 citations in OpenAlex.
- Review
- Light and myopia: a focus on the expanding role of non-visual opsins.Eye and vision (London, England) · 2026Review
- Short-term exposure to cyan light attenuates myopigenic effects of hyperopic defocus on ocular biometry in humans.Scientific reports · 2026Article
- IMI: The Role of Light in Refractive Development and Myopia: Evidence from Animal and Human Studies.Investigative ophthalmology & visual science · 2025Review
- Development of a Hyperopia Animal Model Using Blue Light in Guinea Pigs.Korean journal of ophthalmology : KJO · 2025Article
- Effects of Blue Light Toward Emmetropization.Cureus · 2025Review
- Broadband Long Wavelength Light Promotes Myopic Eye Growth and Alters Retinal Responses to Light Offset in Chick.Investigative ophthalmology & visual science · 2025Article
- The relationship between contact lens ultraviolet light transmittance and myopia progression: a large-scale retrospective cohort study.Precision clinical medicine · 2024Article
- Influence of Aberration-Free, Narrowband Light on the Choroidal Thickness and Eye Length.Translational vision science & technology · 2024Article
- The influence of the environment and lifestyle on myopia.Journal of physiological anthropology · 2024Review
- Effects of Different Spectrum of LEDs on Retinal Degeneration Through Regulating Endoplasmic Reticulum Stress.Translational vision science & technology · 2023Article
- IMI 2023 Digest.Investigative ophthalmology & visual science · 2023Article
- Blue Light Exposure: Ocular Hazards and Prevention-A Narrative Review.Ophthalmology and therapy · 2023Review
- Comment on: "Polymer Co-Coating of Gold Nanoparticles Enables Their Integration Into Contact Lenses for Stable, Selective Ocular Light Filters".Advanced materials interfaces · 2023Article
- Limited bandwidth short-wavelength light produces slowly-developing myopia in tree shrews similar to human juvenile-onset myopia.Vision research · 2023Article
- Effects of endogenous dopamine induced by low concentration atropine eye drops on choroidal neovascularization in high myopia mice.International journal of ophthalmology · 2023Article
- Effects of morning and evening exposures to blue light of varying illuminance on ocular growth rates and ocular rhythms in chicks.Experimental eye research · 2022Article
- Short-Term Exposure to Blue Light Shows an Inhibitory Effect on Axial Elongation in Human Eyes Independent of Defocus.Investigative ophthalmology & visual science · 2021Article
- Effect of Violet Light-Transmitting Eyeglasses on Axial Elongation in Myopic Children: A Randomized Controlled Trial.Journal of clinical medicine · 2021Article
- Long-Wavelength-Filtered Light Transiently Inhibits Negative Lens-Induced Axial Eye Growth in the Chick Myopia Model.Translational vision science & technology · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo analyze the changes of refraction and metabolism of the retinal cones under monochromatic lights in guinea pigs.
methodsSixty guinea pigs were randomly divided into a short-wavelength light (SL) group, a middle-wavelength light (ML) group, and a white light (WL) group. Refraction and axial length were measured before and after 10-week illumination. The densities of S-cones and M-cones were determined by retinal cone immunocytochemistry, and the expressions of S-opsins and M-opsins were determined by real-time PCR and Western blot.
resultsAfter 10-week illumination, the guinea pigs developed relative hyperopia in the SL group and relative myopia in the ML group. Compared with the WL group, the density of S-cones and S-opsins increased while M-cones and M-opsins decreased in the SL group (all,
conclusionsAltered retinal cones/opsins induced by monochromatic lights might be involved in the refractive development in guinea pigs.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.