Evidence map›Paper›PMID 29675239›Full record

ArticleChemical science2018

A luminescent aluminium salen complex allows for monitoring dynamic vesicle trafficking from the Golgi apparatus to lysosomes in living cells.

Juan Tang, Hao-Yan Yin, Jun-Long Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Juan TangBeijing National Laboratory for Molecular Sciences , State Key Laboratory of Rare Earth Materials Chemistry and Applications , College of Chemistry and Molecular Engineering , Peking University , Beijing 100871 , P. R. China . Email: zhangjunlong@pku.edu.cn.
Hao-Yan YinBeijing National Laboratory for Molecular Sciences , State Key Laboratory of Rare Earth Materials Chemistry and Applications , College of Chemistry and Molecular Engineering , Peking University , Beijing 100871 , P. R. China . Email: zhangjunlong@pku.edu.cn.
Jun-Long ZhangBeijing National Laboratory for Molecular Sciences , State Key Laboratory of Rare Earth Materials Chemistry and Applications , College of Chemistry and Molecular Engineering , Peking University , Beijing 100871 , P. R. China . Email: zhangjunlong@pku.edu.cn.ORCID 0000-0002-5731-7354

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Golgi apparatus is well-known as the center of vesicle trafficking whose malfunction might cause the breakdown of overall cellular architecture and ultimately cell death. The development of fluorescent probes to not only precisely stain the Golgi apparatus but also monitor dynamic vesicle trafficking is of great significance. While fluorescent proteins and fluorescent lipid analogs have been reported, they are sometime limited by either overexpression and toxicity or lack of high selectivity, respectively. We herein report a novel approach based on metal-induced coordination between the phosphate anions of phospholipids and the metal center of a luminescent Alsalen complex

Identifiers

PMID29675239
PMCPMC5892405

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.