Evidence map›Paper›PMID 29675109›Full record

ReviewJournal of Cancer2018

Wnt signaling in cervical cancer?

Min Yang, Min Wang, Xianping Li, Yixin Xie, Xiaomeng Xia, Jingjing Tian, Kan Zhang, Aiguo Tang

Open access · goldAbstract readReview
In one paragraph

Review in Journal of Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 88 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
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  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Diagnostic value for methylation in cervical cancer based on a small-molecule fluorescent probe targeting DNMT1.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  14. Article
  15. Inhibition of Wnt/β-catenin signaling by monensin in cervical cancer.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024
    Article
  16. Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Min YangDepartment of Laboratory Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Min WangDepartment of Laboratory Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Xianping LiDepartment of Laboratory Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Yixin XieDepartment of Laboratory Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Xiaomeng XiaDepartment of Obstetrics and Gynecology, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Jingjing TianDepartment of Laboratory Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Kan ZhangDepartment of Laboratory Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Aiguo TangDepartment of Laboratory Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Central South University · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer (CC) is the second most common malignant cancer in women. CC is difficult to diagnose, has a high recurrence rate, and is resistant to systemic therapies; as a result, CC patients have a relatively poor prognosis. One potential link to CC is the Wnt signaling pathway and its downstream effectors, which regulate cell differentiation, proliferation, migration, and fate. The aberrant activation of Wnt signaling is associated with various cancers, including CC. Recent studies have shown that activating or inhibiting the intracellular signal transduction in this pathway can regulate cancer cell growth and viability. This review will summarize the experimental evidence supporting the significance of the Wnt signaling pathway in CC, and will also discuss the current clinical role of Wnt signaling in CC diagnosis, therapy, and prognosis.

Indexed as

CCHPVsignaling pathwayWntβ-catenin

Identifiers

PMID29675109
PMCPMC5907676
OpenAlexW2791389624

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.