Evidence map›Paper›PMID 29674952›Full record

ArticleFrontiers in molecular neuroscience2018

Stability and Function of Hippocampal Mossy Fiber Synapses Depend on

Elodie De Bruyckere, Ruth Simon, Sigrun Nestel, Bernd Heimrich, Dennis Kätzel, Alexei V Egorov, Pentao Liu, Nancy A Jenkins, Neal G Copeland, Herbert Schwegler and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

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  16. Bcl11b/Ctip2 in Skin, Tooth, and Craniofacial System.Frontiers in cell and developmental biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Elodie De BruyckereInstitute of Molecular and Cellular Anatomy, Ulm University, Ulm, Germany.
Ruth SimonInstitute of Molecular and Cellular Anatomy, Ulm University, Ulm, Germany.
Sigrun NestelInstitute of Anatomy and Cell Biology, Faculty of Medicine, Albert-Ludwigs-University, Freiburg, Germany.
Bernd HeimrichInstitute of Anatomy and Cell Biology, Faculty of Medicine, Albert-Ludwigs-University, Freiburg, Germany.
Dennis KätzelInstitute of Applied Physiology, Ulm University, Ulm, Germany.
Alexei V EgorovInstitute of Physiology and Pathophysiology, Heidelberg University, Heidelberg, Germany.
Pentao LiuSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong.
Nancy A JenkinsGenetics Department, University of Texas, MD Anderson Cancer Center, Houston, TX, United States.
Neal G CopelandGenetics Department, University of Texas, MD Anderson Cancer Center, Houston, TX, United States.
Herbert SchweglerInstitute of Anatomy, Otto-von-Guericke-University, Magdeburg, Germany.
Andreas DraguhnInstitute of Physiology and Pathophysiology, Heidelberg University, Heidelberg, Germany.
Stefan BritschInstitute of Molecular and Cellular Anatomy, Ulm University, Ulm, Germany.
Universität Ulm · DEHeidelberg University · DEThe University of Texas MD Anderson Cancer Center · USUniversity of Freiburg · DEOtto-von-Guericke University Magdeburg · DETechnische Hochschule Ulm · DEUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Structural and functional plasticity of synapses are critical neuronal mechanisms underlying learning and memory. While activity-dependent regulation of synaptic strength has been extensively studied, much less is known about the transcriptional control of synapse maintenance and plasticity. Hippocampal mossy fiber (MF) synapses connect dentate granule cells to CA3 pyramidal neurons and are important for spatial memory formation and consolidation. The transcription factor

Indexed as

Bcl11bhippocampusmossy fiber boutonssynapsestranscription factor

Identifiers

PMID29674952
PMCPMC5895709
OpenAlexW2795531881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.